Background: Programmed death ligand-1 (PD-L1) functions as a negative mediator of
immune response through different pathways in anti-tumor immunity. Recent studies have …

Developments in new information technology have indicated that single manufacturing
services are now unable to satisfy users’ multi-objective demands, especially in the process …

Original research: Frequent amplification of HDAC genes and efficacy of HDAC inhibitor
chidamide and PD-1 blockade combination in soft tissue sarcoma - PMC Back to Top Skip to …

New York esophageal squamous cell carcinoma-1 (NY-ESO-1)-specific T cell receptor (TCR)
T cell therapy is effective in tumors with NY-ESO-1 expression, but a safe and effective TCR…

Background Inflammation can promote tumor growth, invasion, angiogenesis and even
metastasis. Inflammatory markers have been identified as prognostic indicators in various …

Objective To elucidate the role and prognostic significance of lymphocyte activation-gene-3 (LAG-3)
in soft tissue sarcoma (STS). Methods The expression of LAG-3 in patient and …

Ewing sarcoma (EwS) is an aggressive tumor that affects children and young adults. Patients
with relapsed/refractory diseases have limited treatment options. Targeting the driver fusion …

Background Coagulation and nutrition play important roles in cancer progression. The aim
of the present study is to evaluate the prognostic value of the preoperative fibrinogen/albumin …

The thermal performance of thermosyphon flat-plate solar water heater with a mantle heat
exchanger was investigated to show its applicability in China. The effect on the performance of …

Neuroblastoma (NB) is the most common extracranial solid malignancy in children and its
mortality rate is relatively high. However, driver genes of NB are not clearly identified. Using …