MicroRNAs are non-coding small RNAs that regulate gene expression by Watson–Crick
base pairing to target messenger RNA (mRNA). They are involved in most biological and …

Evidences have been provided that long noncoding RNAs (lncRNAs) act as key molecules
in epigenetic regulation and are involved in the development process of cancer in recent …

Leiomyosarcoma is a malignant mesenchymal tumor composed of cells showing smooth
muscle differentiation. This tumor usually occurs in middle-aged or older adults, and forms a …

Background: The aim of the study was to improve the diagnosis and treatment of retroperitoneal
schwannoma by analysing clinical manifestations and postoperative course of this rare …

Somatic mutations and large‐scale depletion in mitochondrial DNA (mtDNA) have been
extensively detected in various human cancers. However, it still remains unclear whether the …

HOX transcript antisense RNA (HOTAIR), a long intergenic non-coding RNA (lncRNA), functions
as a molecular scaffold to link and target the histone modification complexes PRC2 and …

Vasculogenic mimicry (VM) has increasingly been recognized as a form of angiogenesis. In
VM, epithelial cells are integrated into the malignant tumor vasculature. An association has …

BACKGROUND Metastatic disease is a major adverse prognostic factor in breast carcinoma.
Lymph node metastases often represent the first step in the metastatic process. METHODS …

Background Experimental evidence suggests that matrix metalloproteinase-13 (MMP-13)
protein may promote breast tumor progression, however, its role is yet to be fully established. …

Purpose: The therapeutic benefit of the cytokine-induced killer (CIK) cells was unknown in
the renal cell carcinoma (RCC). This prospectively randomized study was conducted to …