User profiles for Xiaoyuan Chen

Xiaoyuan (Shawn) Chen

National University of Singapore
Verified email at nus.edu.sg
Cited by 142132

High-thermoelectric performance of nanostructured bismuth antimony telluride bulk alloys

…, D Vashaee, X Chen, J Liu, MS Dresselhaus, G Chen… - science, 2008 - science.org
The dimensionless thermoelectric figure of merit (ZT) in bismuth antimony telluride (BiSbTe)
bulk alloys has remained around 1 for more than 50 years. We show that a peak ZT of 1.4 at …

Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer

Y Liu, P Bhattarai, Z Dai, X Chen - Chemical Society Reviews, 2019 - pubs.rsc.org
The nonradiative conversion of light energy into heat (photothermal therapy, PTT) or sound
energy (photoacoustic imaging, PAI) has been intensively investigated for the treatment and …

Carbon nanotubes as photoacoustic molecular imaging agents in living mice

…, BR Smith, TJ Ma, O Oralkan, Z Cheng, X Chen… - Nature …, 2008 - nature.com
Photoacoustic imaging of living subjects offers higher spatial resolution and allows deeper
tissues to be imaged compared with most optical imaging techniques 1 , 2 , 3 , 4 , 5 , 6 , 7 . As …

In vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice

…, L He, N Nakayama, K Chen, X Sun, X Chen… - Nature …, 2007 - nature.com
Single-walled carbon nanotubes (SWNTs) exhibit unique size, shape and physical
properties 1 , 2 , 3 that make them promising candidates for biological applications. Here, we …

[HTML][HTML] Upconversion nanoparticles: design, nanochemistry, and applications in theranostics

G Chen, H Qiu, PN Prasad, X Chen - Chemical reviews, 2014 - ACS Publications
Theranostics is a concept of integrating imaging and therapy into a single platform for use in
the next generation of personalized medicine to meet the challenges in modern health care.(…

Particle size, surface coating, and PEGylation influence the biodistribution of quantum dots in living mice

…, A Aharoni, S Keren, LA Bentolila, J Li, J Rao, X Chen… - Small, 2009 - Wiley Online Library
This study evaluates the influence of particle size, PEGylation, and surface coating on the
quantitative biodistribution of near‐infrared‐emitting quantum dots (QDs) in mice. Polymer‐ or …

Drug Delivery with Carbon Nanotubes for In vivo Cancer Treatment

Z Liu, K Chen, C Davis, S Sherlock, Q Cao, X Chen… - Cancer research, 2008 - AACR
Chemically functionalized single-walled carbon nanotubes (SWNT) have shown promise in
tumor-targeted accumulation in mice and exhibit biocompatibility, excretion, and little toxicity. …

Clinical development and potential of photothermal and photodynamic therapies for cancer

X Li, JF Lovell, J Yoon, X Chen - Nature reviews Clinical oncology, 2020 - nature.com
Light-activated, photosensitizer-based therapies have been established as safe modalities
of tumour ablation for numerous cancer indications. Two main approaches are available: …

Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature

…, K Chen, ZB Li, SS Gambhir, X Chen - Journal of Nuclear …, 2007 - Soc Nuclear Med
To date, the in vivo imaging of quantum dots (QDs) has been mostly qualitative or semiquantitative.
The development of a dual-function PET/near-infrared fluorescence (NIRF) probe …

Nanoparticle-based theranostic agents

J Xie, S Lee, X Chen - Advanced drug delivery reviews, 2010 - Elsevier
Theranostic nanomedicine is emerging as a promising therapeutic paradigm. It takes advantage
of the high capacity of nanoplatforms to ferry cargo and loads onto them both imaging …