Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis

A Suzuki, R Yamada, X Chang, S Tokuhiro, T Sawada… - Nature …, 2003 - nature.com
Individuals with rheumatoid arthritis frequently have autoantibodies to citrullinated peptides,
suggesting the involvement of the peptidylarginine deiminases citrullinating enzymes (…

Gonadal sex differentiation in teleost fish.

M Nakamura, T Kobayashi, CXT Chang XiaoTian… - 1998 - cabidigitallibrary.org
A review. The differentiation of gonads in gonochoristic fish species is discussed under that
following headings: Gonadal primordia in fish; Initial ovarian and testicular differentiation; …

An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis

S Tokuhiro, R Yamada, X Chang, A Suzuki, Y Kochi… - Nature …, 2003 - nature.com
Rheumatoid arthritis is a common inflammatory disease with complex genetic components.
We investigated the genetic contribution of the cytokine gene cluster in chromosome 5q31 to …

A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities

…, T Sawada, SC Bae, S Tokuhiro, X Chang… - Nature …, 2005 - nature.com
Rheumatoid arthritis is a common autoimmune disease with a complex genetic etiology. Here
we identify a SNP in the promoter region of FCRL3, a member of the Fc receptor-like family…

Increased PADI4 expression in blood and tissues of patients with malignant tumors

X Chang, J Han, L Pang, Y Zhao, Y Yang, Z Shen - BMC cancer, 2009 - Springer
Background Peptidylarginine deiminase type 4 (PAD4/PADI4) post-translationally converts
peptidylarginine to citrulline. Recent studies suggest that PADI4 represses expression of p53-…

Expression of peptidylarginine deiminase type 4 (PAD4) in various tumors

X Chang, J Han - … : Published in cooperation with the University …, 2006 - Wiley Online Library
Peptidylarginine deiminase type 4 (PAD4/PADI4) posttranslationally converts peptidylarginine
to citrulline, in a process known as citrullination. Evidence suggests that PAD4 plays an …

Two types of aromatase with different encoding genes, tissue distribution and developmental expression in Nile tilapia (Oreochromis niloticus)

X Chang, T Kobayashi, B Senthilkumaran… - General and …, 2005 - Elsevier
We isolated a novel type of aromatase cDNA from a Nile tilapia (Oreochromis niloticus)
ovary cDNA library. Because this aromatase is phylogenetically related to brain aromatase (…

Glycolysis and rheumatoid arthritis

X Chang, C Wei - International journal of rheumatic diseases, 2011 - Wiley Online Library
Glucose metabolism not only provides energy for physical activity but also mediates a variety
of physiological processes through the formation of complex signalling networks. Recent …

Identification of proteins with increased expression in rheumatoid arthritis synovial tissues

X Chang, Y Cui, M Zong, Y Zhao, X Yan… - The Journal of …, 2009 - jrheum.org
Objective. A proteomic approach was applied to discover novel rheumatoid arthritis (RA)-specific
proteins by comparing the expression profiles of synovial membranes from patients …

Gaussian Differential Privacy on Riemannian Manifolds

Y Jiang, X Chang, Y Liu, L Ding… - Advances in Neural …, 2023 - proceedings.neurips.cc
We develop an advanced approach for extending Gaussian Differential Privacy (GDP) to
general Riemannian manifolds. The concept of GDP stands out as a prominent privacy …