User profiles for Xiaoming Cheng

Xiaoming Cheng

Wuhan University
Verified email at whu.edu.cn
Cited by 3205

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

…, X Liu, G Gao, F Liu, Y Jiang, X Cheng… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild, …

Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA

…, Y Xia, F Reisinger, K Zhang, D Stadler, X Cheng… - Science, 2014 - science.org
Current antiviral agents can control but not eliminate hepatitis B virus (HBV), because HBV
establishes a stable nuclear covalently closed circular DNA (cccDNA). Interferon-α treatment …

IL-17 is associated with poor prognosis and promotes angiogenesis via stimulating VEGF production of cancer cells in colorectal carcinoma

J Liu, Y Duan, X Cheng, X Chen, W Xie, H Long… - Biochemical and …, 2011 - Elsevier
IL-17, which exerts strong pro-inflammatory effects, has emerged as an important mediator
in inflammation-associated cancer. However, the characteristics of IL-17-producing cells, the …

Interferon-γ and tumor necrosis factor-α produced by T cells reduce the HBV persistence form, cccDNA, without cytolysis

…, D Webb, M Hösel, T Michler, K Wisskirchen, X Cheng… - Gastroenterology, 2016 - Elsevier
Background & Aims Viral clearance involves immune cell cytolysis of infected cells. However,
studies of hepatitis B virus (HBV) infection in chimpanzees have indicated that cytokines …

Activity-dependent synaptic plasticity of a chalcogenide electronic synapse for neuromorphic systems

…, J Zhang, L Xu, Q Wang, H Sun, H Tong, X Cheng… - Scientific reports, 2014 - nature.com
Nanoscale inorganic electronic synapses or synaptic devices, which are capable of emulating
the functions of biological synapses of brain neuronal systems, are regarded as the basic …

[PDF][PDF] Hepatitis B virus evades innate immunity of hepatocytes but activates cytokine production by macrophages

X Cheng, Y Xia, E Serti, PD Block, M Chung… - …, 2017 - Wiley Online Library
Hepatitis B virus (HBV) infects hepatocytes specifically and causes immune‐mediated liver
damage. How HBV interacts with the innate immunity at the early phase of infection, either …

Metformin inhibits the IL-6-induced epithelial-mesenchymal transition and lung adenocarcinoma growth and metastasis

Z Zhao, X Cheng, Y Wang, R Han, L Li, T Xiang, L He… - PloS one, 2014 - journals.plos.org
Objective Epithelial-mesenchymal transition (EMT) plays an important role in cancer tumorigenesis.
However, the underlying mechanisms of EMT in lung adenocarcinoma, and how this …

Human stem cell-derived hepatocytes as a model for hepatitis B virus infection, spreading and virus-host interactions

Y Xia, A Carpentier, X Cheng, PD Block, Y Zhao… - Journal of …, 2017 - Elsevier
Background & Aims One major obstacle of hepatitis B virus (HBV) research is the lack of
efficient cell culture system permissive for viral infection and replication. The aim of our study …

Clinical characteristics of COVID‐19 patients with hepatitis B virus infection—a retrospective study

R Liu, L Zhao, X Cheng, H Han, C Li, D Li… - Liver …, 2021 - Wiley Online Library
Background & Aims The outbreak of coronavirus disease 2019 (COVID‐19) has been
declared a pandemic. Although COVID‐19 is caused by infection in the respiratory tract, …

Monotonic behavior of interface shear between carbonate sands and steel

S Rui, L Wang, Z Guo, X Cheng, B Wu - Acta Geotechnica, 2021 - Springer
The characteristic of interface shear between carbonate sands and steel is important for the
design of onshore/offshore foundations in coral reef deposit. By using an interface ring shear …