Ionizing radiation-mediated tumor regression depends on type I interferon (IFN) and the
adaptive immune response, but several pathways control I IFN induction. Here, we demonstrate …

Hepatitis C virus (HCV) is a global epidemic manifested mainly by chronic infection. One
strategy that HCV employs to establish chronic infection is to use the viral Ser protease NS3/4A …

… Li Miao (李淼) 1,2 , Li Xiao-Dong (李霄栋) 2,3 , Wang Shuang (王爽) 2,3 and Wang Yi (王一
) 4 … Communications in Theoretical Physics, Volume 56, Number 3 Citation Li Miao et al …

Inhibition of cytosolic DNA sensing represents a strategy that tumor cells use for immune
evasion, but the underlying mechanisms are unclear. Here we have shown that CD47-signal …

Invasion of microbial DNA into the cytoplasm of animal cells triggers a cascade of host
immune reactions that help clear the infection; however, self DNA in the cytoplasm can cause …

TREX1 is an exonuclease that digests DNA in the cytoplasm. Loss-of-function mutations of
TREX1 are linked to Aicardi–Goutieres Syndrome (AGS) and systemic lupus erythematosus (…

The spread of HIV between immune cells is greatly enhanced by cell-cell adhesions called
virological synapses, although the underlying mechanisms have been unclear. With use of …

Activation of the DNA-dependent cytosolic surveillance pathway in response to Mycobacterium
tuberculosis infection stimulates ubiquitin-dependent autophagy and inflammatory …

The holographic principle of quantum gravity theory has been applied to the dark energy (DE)
problem, and so far three holographic DE models have been proposed: the original …

Curcumin (diferuloylmethane), is a natural chemopreventive agent known to inhibit the
proliferation of several cancer cell lines. It has been previously demonstrated that curcumin is a …