In-silico investigation of umami peptides with receptor T1R1/T1R3 for the discovering potential targets: A combined modeling approach
W Wang, Z Cui, M Ning, T Zhou, Y Liu - Biomaterials, 2022 - Elsevier
Umami, providing amino acids/peptides for animal growth, represents one of the major
attractive taste modalities. The biochemical and umami properties of peptide are both important …
attractive taste modalities. The biochemical and umami properties of peptide are both important …
[HTML][HTML] Irbesartan overcomes gemcitabine resistance in pancreatic cancer by suppressing stemness and iron metabolism via inhibition of the Hippo/YAP1/c-Jun axis
T Zhou, Y Xie, X Hou, W Bai, X Li, Z Liu, Q Man… - Journal of Experimental …, 2023 - Springer
Background Chemoresistance is the main reason for the poor prognosis of pancreatic ductal
adenocarcinoma (PDAC). Thus, there is an urgent need to screen out new targets and …
adenocarcinoma (PDAC). Thus, there is an urgent need to screen out new targets and …
ESE3/EHF, a promising target of rosiglitazone, suppresses pancreatic cancer stemness by downregulating CXCR4
T Zhou, J Liu, Y Xie, S Yuan, Y Guo, W Bai, K Zhao… - Gut, 2022 - gut.bmj.com
Background and aims The crosstalk between cancer stem cells (CSCs) and their niche is
required for the maintenance of stem cell-like phenotypes of CSCs. Here, we identified E26 …
required for the maintenance of stem cell-like phenotypes of CSCs. Here, we identified E26 …
Progress in the change of ash melting behavior and slagging characteristics of co-gasification of biomass and coal: A review
T Zhou, W Zhang, Y Shen, S Luo, D Ren - Journal of the Energy Institute, 2023 - Elsevier
The gasification process is considered one of the most effective methods for harnessing
energy from biomass. As a promising renewable energy source, biomass offers energy-saving, …
energy from biomass. As a promising renewable energy source, biomass offers energy-saving, …
[HTML][HTML] Tumoral EHF predicts the efficacy of anti-PD1 therapy in pancreatic ductal adenocarcinoma
J Liu, W Jiang, K Zhao, H Wang, T Zhou… - Journal of Experimental …, 2019 - rupress.org
Pancreatic ductal adenocarcinoma (PDAC) is a highly immune-suppressive tumor with a
low response rate to single checkpoint blockade therapy. ETS homologous factor (EHF) is a …
low response rate to single checkpoint blockade therapy. ETS homologous factor (EHF) is a …
All-in-one second near-infrared light-responsive drug delivery system for synergistic chemo-photothermal therapy
T Zhou, S Xie, C Zhou, Y Chen, H Li, P Liu… - ACS Applied Bio …, 2022 - ACS Publications
Light-responsive nanocarrier-based drug delivery systems (NDDSs), due to their unique
advantages such as safety, minimal cross-reaction, and spatiotemporal precision, have …
advantages such as safety, minimal cross-reaction, and spatiotemporal precision, have …
Conserved sites and recognition mechanisms of T1R1 and T2R14 receptors revealed by ensemble docking and molecular descriptors and fingerprints combined with …
Z Cui, N Zhang, T Zhou, X Zhou, H Meng… - Journal of Agricultural …, 2023 - ACS Publications
Taste peptides, as an important component of protein-rich foodstuffs, potentiate the nutrition
and taste of food. Thereinto, umami- and bitter-taste peptides have been ex tensively …
and taste of food. Thereinto, umami- and bitter-taste peptides have been ex tensively …
A TastePeptides-Meta system including an umami/bitter classification model Umami_YYDS, a TastePeptidesDB database and an open-source package …
Z Cui, Z Zhang, T Zhou, X Zhou, Y Zhang, H Meng… - Food Chemistry, 2023 - Elsevier
Taste peptides with umami/bitterness play a role in food attributes. However, the taste
mechanisms of peptides are not fully understood, and the identification of these peptides is time-…
mechanisms of peptides are not fully understood, and the identification of these peptides is time-…
Gold nanobipyramid@ copper sulfide nanotheranostics for image-guided NIR-II photo/chemodynamic cancer therapy with enhanced immune response
Y Chen, P Liu, C Zhou, T Zhang, T Zhou, D Men… - Acta Biomaterialia, 2023 - Elsevier
Photothermal therapy (PTT), photodynamic therapy (PDT), and chemodynamic therapy (CDT)
can cause cancer cell death through an immunogenic process. However, the study of …
can cause cancer cell death through an immunogenic process. However, the study of …
A robust, integrated platform for comprehensive analyses of acyl-coenzyme As and acyl-carnitines revealed chain length-dependent disparity in fatty acyl metabolic …
Acyl-coenzyme A thioesters (acyl-CoAs) denote a key class of intermediary metabolites that
lies at the hub of major metabolic pathways. The great diversity in polarity between short- …
lies at the hub of major metabolic pathways. The great diversity in polarity between short- …