MicroRNAs are ∼21nt single-stranded RNAs and function as regulators of gene expression.
Previous studies have shown that microRNAs play crucial roles in tumorigenesis by …

MicroRNAs have been linked to different cancer-related processes. The microRNA miR-21
appears to function as an anti-apoptosis factor in glioblastomas. However, the functional …

Migration-proliferation dichotomy is a common mechanism in gliomagenesis; however, an
understanding of the exact molecular mechanism of this “go or grow” phenomenon remains …

miR-214 is involved in numerous physiological and pathological processes including
tumorigenesis. However, the function of miR-214 in the development and treatment of breast …

Cancer is a top global public health concern. At present, molecular targeted therapy has
emerged as one of the main therapies for cancer, with high efficacy and safety. The medical …

Immunomodulatory effects of long-chain fatty acids (LCFAs) and their activating enzyme,
acyl-coenzyme A (CoA) synthetase long-chain family (ACSL), in the tumor microenvironment …

The tumour suppressor p53 transactivates the expression of its target genes to exert its
functions. Here, we identify a pleckstrin homology domain-containing protein (PHLDB3)-…

MicroRNAs are a class of small endogenous noncoding RNAs which play important regulatory
roles mainly by post-transcriptional depression. Finding miRNA target genes will help a …

Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are being widely
used as targeted therapy in non-small cell lung cancer (NSCLC), but most cases acquire drug-…

Pneumonitis is a rare but severe and potentially fatal adverse effect in chemotherapy of
lymphoma. This study is aimed to investigate the incidence of interstitial pneumonitis in non-…