[HTML][HTML] The resistance mechanisms of proteasome inhibitor bortezomib
S Lü, J Wang - Biomarker research, 2013 - Springer
The proteasome inhibitor, bortezomib, a boronic dipeptide which reversibly inhibit the
chymotrypsin-like activity at the β5-subunit of proteasome (PSMB5), has marked efficacy against …
chymotrypsin-like activity at the β5-subunit of proteasome (PSMB5), has marked efficacy against …
[HTML][HTML] Homoharringtonine and omacetaxine for myeloid hematological malignancies
S Lü, J Wang - Journal of hematology & oncology, 2014 - Springer
Homoharringtonine (HHT), a plant alkaloid with antitumor properties originally identified nearly
40 years ago, has a unique mechanism of action by preventing the initial elongation step …
40 years ago, has a unique mechanism of action by preventing the initial elongation step …
[HTML][HTML] Overexpression of the PSMB5 gene contributes to bortezomib resistance in T-lymphoblastic lymphoma/leukemia cells derived from Jurkat line
S Lü, Z Chen, J Yang, L Chen, S Gong, H Zhou… - Experimental …, 2008 - Elsevier
OBJECTIVE: To study the mechanism of bortezomib resistance in JurkatB lines derived from
T-lymphoblastic lymphoma/leukemia Jurkat line. MATERIALS AND METHODS: …
T-lymphoblastic lymphoma/leukemia Jurkat line. MATERIALS AND METHODS: …
[HTML][HTML] Different mutants of PSMB5 confer varying bortezomib resistance in T lymphoblastic lymphoma/leukemia cells derived from the Jurkat cell line
S Lü, J Yang, Z Chen, S Gong, H Zhou, X Xu… - Experimental …, 2009 - Elsevier
OBJECTIVE: To investigate the relationship between bortezomib resistance and mutations
in the proteasome β5 subunit (PSMB5) gene. MATERIALS AND METHODS: Various …
in the proteasome β5 subunit (PSMB5) gene. MATERIALS AND METHODS: Various …
Reversibly Thermo-Responsive Materials Applied in Lithium Batteries
Z Wei, L Yu, S Lu, Y Zhao - Energy Storage Materials, 2023 - Elsevier
Thermo-responsive materials are smart materials that are capable of reacting to a local
temperature variation, with high stimuli-sensitivity and/or facile reversibility. In recent years, …
temperature variation, with high stimuli-sensitivity and/or facile reversibility. In recent years, …
[PDF][PDF] Point mutation of the proteasome b5 subunit gene is an important mechanism of bortezomib resistance in bortezomib-selected variants of Jurkat T cell …
S Lu, J Yang, X Song, S Gong, H Zhou, L Guo… - J Pharmacol Exp …, 2008 - Citeseer
To study the mechanism of acquired resistance to bortezomib, a new antitumor drug that is
the first therapeutic proteasome inhibitor, we established a series of bortezomib-resistant T …
the first therapeutic proteasome inhibitor, we established a series of bortezomib-resistant T …
[HTML][HTML] Clinical and biological characteristics of adult biphenotypic acute leukemia in comparison with that of acute myeloid leukemia and acute lymphoblastic …
XQ Xu, JM Wang, SQ Lü, L Chen, JM Yang… - …, 2009 - ncbi.nlm.nih.gov
Background Biphenotypic acute leukemia is a rare disorder that is difficult to diagnose. It
displays features of both myeloid and lymphoid lineage. There is still a lack of studies in …
displays features of both myeloid and lymphoid lineage. There is still a lack of studies in …
Upregulated expression of the PSMB5 gene may contribute to drug resistance in patient with multiple myeloma when treated with bortezomib-based regimen
L Shuqing, Y Jianmin, H Chongmei, C Hui… - Experimental …, 2011 - exphem.org
Multiple myeloma (MM) is a hematological malignancy of which complete response (CR) is
rarely achieved by routine chemotherapy. Proteasome inhibitors have been recognized as a …
rarely achieved by routine chemotherapy. Proteasome inhibitors have been recognized as a …
Characteristics of acute myeloid leukemia with myelodysplasia‐related changes: a retrospective analysis in a cohort of Chinese patients
…, XX Hu, JM Yang, X Ni, J Chen, SQ Lü… - American journal of …, 2014 - Wiley Online Library
We retrospectively analyzed 449 patients with AML under the WHO classification of AML 2008
and probed implications of this classification in diagnosis and treatment of acute myeloid …
and probed implications of this classification in diagnosis and treatment of acute myeloid …
Point mutation of the proteasome β5 subunit gene is an important mechanism of bortezomib resistance in bortezomib-selected variants of Jurkat T cell lymphoblastic …
S Lü, J Yang, X Song, S Gong, H Zhou, L Guo… - … of Pharmacology and …, 2008 - ASPET
To study the mechanism of acquired resistance to bortezomib, a new antitumor drug that is
the first therapeutic proteasome inhibitor, we established a series of bortezomib-resistant T …
the first therapeutic proteasome inhibitor, we established a series of bortezomib-resistant T …