Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin

…, S Sui, L Wang, H Li, L Zhang, S Xu… - Journal of Cellular …, 2020 - Wiley Online Library
Glutathione peroxidase 4 (GPX4) has been confirmed to inhibit ferroptosis in cancer cells,
however, whether GPX4 serves as an oncogene is not clear. In this study, the expression of …

Inspired by Stenocara Beetles: From Water Collection to High-Efficiency Water-in-Oil Emulsion Separation

X Zeng, L Qian, X Yuan, C Zhou, Z Li, J Cheng, S Xu… - ACS …, 2017 - ACS Publications
Inspired by the water-collecting mechanism of the Stenocara beetle’s back structure, we
prepared a superhydrophilic bumps–superhydrophobic/superoleophilic stainless steel mesh (…

Oncogenic long noncoding RNA landscape in breast cancer

S Xu, D Kong, Q Chen, Y Ping, D Pang - Molecular cancer, 2017 - Springer
Background Few long noncoding RNAs (lncRNAs) that act as oncogenic genes in breast
cancer have been identified. Methods Oncogenic lncRNAs associated with tumourigenesis and …

Superhydrophilic and underwater superoleophobic titania nanowires surface for oil repellency and oil/water separation

…, J Cheng, K Hou, A Zhao, P Pi, X Wen, S Xu - Chemical Engineering …, 2016 - Elsevier
Superhydrophilic and underwater superoleophobic titania nanowires (TNWs) films on Ti
substrates were fabricated via a facile low temperature and short time-consuming route. The …

[HTML][HTML] Downregulation of long noncoding RNA MALAT1 induces epithelial-to-mesenchymal transition via the PI3K-AKT pathway in breast cancer

S Xu, S Sui, J Zhang, N Bai, Q Shi… - … journal of clinical and …, 2015 - ncbi.nlm.nih.gov
The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) regulates cell
motility via the transcriptional or post-transcriptional control of motility-related genes. Whether …

Emerging role of ferroptosis in breast cancer: New dawn for overcoming tumor progression

S Sui, S Xu, D Pang - Pharmacology & Therapeutics, 2022 - Elsevier
Breast cancer has become a serious threat to women's health. Cancer progression is mainly
derived from resistance to apoptosis induced by procedures or therapies. Therefore, new …

Ferritinophagy is required for the induction of ferroptosis by the bromodomain protein BRD4 inhibitor (+)-JQ1 in cancer cells

S Sui, J Zhang, S Xu, Q Wang, P Wang, D Pang - Cell death & disease, 2019 - nature.com
(+)-JQ1 is an inhibitor of the tumor-driver bromodomain protein BRD4 and produces satisfactory
effects because it efficiently increases apoptosis. Ferroptosis is an oxidative cell death …

LINC00673 is activated by YY1 and promotes the proliferation of breast cancer cells via the miR-515-5p/MARK4/Hippo signaling pathway

…, S Ning, L Wan, H Wu, Q Wang, X Zhang, S Xu… - Journal of Experimental …, 2019 - Springer
Background An increasing number of studies have shown that long noncoding RNAs (lncRNAs)
play essential roles in tumor initiation and progression. LncRNAs act as tumor …

LncRNA TINCR impairs the efficacy of immunotherapy against breast cancer by recruiting DNMT1 and downregulating MiR-199a-5p via the STAT1–TINCR-USP20 …

…, Y Chen, X Zhang, L Zhang, L Sun, J Ai, S Xu - Cell death & …, 2023 - nature.com
Although programmed death-ligand 1 (PD-L1) inhibitors have achieved some therapeutic
success in breast cancer, their efficacy is limited by low therapeutic response rates, which is …

PSAT1 is regulated by ATF4 and enhances cell proliferation via the GSK3β/β-catenin/cyclin D1 signaling pathway in ER-negative breast cancer

S Gao, A Ge, S Xu, Z You, S Ning, Y Zhao… - Journal of Experimental & …, 2017 - Springer
Background A growing amount of evidence has indicated that PSAT1 is an oncogene that
plays an important role in cancer progression and metastasis. In this study, we explored the …