Nuclear GRP78 promotes metabolic reprogramming and therapeutic resistance in pancreatic ductal adenocarcinoma

T Zhao, T Jiang, X Li, S Chang, Q Sun, F Kong… - Clinical Cancer …, 2023 - AACR
Purpose: Stromal fibrosis limits nutritional supply and disarrays metabolism in pancreatic
cancer (PDA, pancreatic ductal adenocarcinoma). Understanding of the molecular basis …

[HTML][HTML] Presence of tumor deposits is an indicator of poor prognosis in patients with pancreatic ductal adenocarcinoma

Y Liang, S Chang, H Guo, Q Man, F Zang… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Tumor deposits (TDs) are associated with poor prognosis in several malignancies and have
been incorporated into the tumor-node-metastasis (TNM) staging system for colorectal …

Prognostic nutritional score based on pretreatment lymphocyte, platelet, and prealbumin predicts prognosis in patients with pancreatic cancer

Y Liang, H Guo, Q Man, S Chang… - Journal of Surgical …, 2023 - Wiley Online Library
Background and Objectives Pretreatment immunological indicators and nutritional factors
are associated with survival of many malignancies. This study aims to develop a prognostic …

[PDF][PDF] A new staging system for postoperative prognostication in pancreatic ductal adenocarcinoma

Y Liang, J Cui, F Ding, Y Zou, H Guo, Q Man, S Chang… - Iscience, 2023 - cell.com
The current TNM staging system for pancreatic ductal adenocarcinoma (PDAC) has revised
the definitions of T and N categories as well as stage groups. However, studies validating …

Elevated preoperative plasma D-dimer level was an independent prognostic factor for patients with PDAC after curative resection: a retrospective analysis

L Zhifei, L Yuexiang, C Shaofei, L Shuo… - Japanese Journal of …, 2023 - academic.oup.com
Objective In this study, the relationship between preoperative plasma D-dimer level and overall
survival and recurrence free survival were evaluated in patients with curative resection of …

[HTML][HTML] Comparison of adjuvant nab-paclitaxel plus gemcitabine, S-1 and gemcitabine chemotherapy for resectable pancreatic cancer: a real-world study

H Li, Y Guo, X Sun, Y Lu, S Chang, X Wang… - Frontiers in …, 2023 - ncbi.nlm.nih.gov
Background A survival benefit has been seen for both adjuvant nab-paclitaxel plus gemcitabine
(AG) and S-1 chemotherapy compared to gemcitabine (GEM) for resectable pancreatic …

[HTML][HTML] Prognostic significance of grade of malignancy based on histopathological differentiation and Ki-67 in pancreatic ductal adenocarcinoma

…, Y Guo, Y Zou, H Guo, Z Li, S Chang… - Cancer Biology & …, 2024 - cancerbiomed.org
Objective: Tumor cell malignancy is indicated by histopathological differentiation and cell
proliferation. Ki-67, an indicator of cellular proliferation, has been used for tumor grading and …

Biological risk based on preoperative serum CA19‐9 and histological grade predicts prognosis and improves accuracy of classification in patients with pancreatic …

S Chang, Y Liu, Y Liang, Q Man, H Li, Y Guo… - Cancer …, 2023 - Wiley Online Library
Background Carbohydrate antigen (CA) 19‐9 and histological grade can serve as indicators
of the biological characteristics of pancreatic ductal adenocarcinoma (PDAC). Aims The aim …

[HTML][HTML] Nomogram model for predicting early recurrence for resectable pancreatic cancer: A multicenter study

Q Man, H Pang, Y Liang, S Chang, J Wang, S Gao - Medicine, 2024 - journals.lww.com
Pancreatic cancer is a highly aggressive malignancy that is characterized by early metastasis,
high recurrence, and therapy resistance. Early recurrence after surgery is one of the …

[PDF][PDF] Lysophosphatidylcholine acyltransferase 1 is involved in the regulation of exosome secretion and uptake in colorectal cancer cells

H Liu, S Chang - Biocell, 2022 - cdn.techscience.cn
… HAIZHENG LIU1; SHAOFEI CHANG2,* … They are widely distributed and *Address
correspondence to: Shaofei Chang, sy4960343@163.com Received: 10 December 2020; …