Elevated preoperative neutrophil to lymphocyte ratio predicts risk of recurrence following curative resection for stage IIA colon cancer

PR Ding, X An, RX Zhang, YJ Fang, LR Li… - International journal of …, 2010 - Springer
Background and Objectives Adjuvant chemotherapy for stage II colon cancer remains
controversial but may be considered for patients with high-risk features. Recent studies have …

[HTML][HTML] LncRNA HULC enhances epithelial-mesenchymal transition to promote tumorigenesis and metastasis of hepatocellular carcinoma via the miR-200a-3p/ZEB1 …

…, YJ Xu, CY Wang, HM Zhang, RX Zhang, JJ Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Highly upregulated in liver cancer (HULC), a lncRNA that is considered a key molecule in
human liver cancer, has recently been revealed to be involved in hepatocellular carcinoma (…

[HTML][HTML] Tumor-induced myeloid-derived suppressor cells promote tumor progression through oxidative metabolism in human colorectal cancer

LY OuYang, XJ Wu, SB Ye, R Zhang, ZL Li… - Journal of translational …, 2015 - Springer
Background Expansions of myeloid-derived suppressor cells (MDSCs) have been identified
in human solid tumors, including colorectal cancer (CRC). However, the nature of these …

Neoadjuvant PD-1 blockade with sintilimab in mismatch-repair deficient, locally advanced rectal cancer: an open-label, single-centre phase 2 study

G Chen, Y Jin, WL Guan, RX Zhang… - The Lancet …, 2023 - thelancet.com
Background The current standard treatment for locally advanced rectal cancer is neoadjuvant
chemoradiotherapy followed by radical surgery, but this approach can lead to multiple …

Curcumin inhibits melanogenesis in human melanocytes

…, SS Lu, XY Qi, RX Zhang, YY Zhang - Phytotherapy …, 2012 - Wiley Online Library
Plant derived compounds, as potentially safe and effective skin lightening agents (SLAs), have
attracted great attention from many researchers. Curcumin is a plant‐derived polyphenol, …

[HTML][HTML] CMTM6 and PD-L1 coexpression is associated with an active immune microenvironment and a favorable prognosis in colorectal cancer

QH Peng, CH Wang, HM Chen, RX Zhang… - … for Immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Original research: CMTM6 and PD-L1 coexpression is associated with an active immune
microenvironment and a favorable prognosis in colorectal cancer - PMC Back to Top Skip to …

Medium-chain triglyceride activated brown adipose tissue and induced reduction of fat mass in C57BL/6J mice fed high-fat diet

Y Zhang, XU Qing, YH Liu, XS Zhang, W Jin… - Biomedical and …, 2015 - Elsevier
Objective To investigate activation of brown adipose tissue (BAT) stimulated by medium-chain
triglyceride (MCT). Methods 30 Male C57BL/6J obese mice induced by fed high fat diet (…

Genome-wide RNAi screening identifies RFC4 as a factor that mediates radioresistance in colorectal cancer by facilitating nonhomologous end joining repair

XC Wang, X Yue, RX Zhang, TY Liu, ZZ Pan… - Clinical Cancer …, 2019 - AACR
Purpose: Neoadjuvant chemoradiotherapy (neoCRT) is a standard treatment for locally
advanced rectal cancer (LARC); however, resistance to chemoradiotherapy is one of the main …

Machine learning models in type 2 diabetes risk prediction: results from a cross-sectional retrospective study in Chinese adults

X Xiong, R Zhang, Y Bi, W Zhou, Y Yu, D Zhu - Current medical science, 2019 - Springer
Type 2 diabetes mellitus (T2DM) has become a prevalent health problem in China, especially
in urban areas. Early prevention strategies are needed to reduce the associated mortality …

[HTML][HTML] Vitexin suppresses autophagy to induce apoptosis in hepatocellular carcinoma via activation of the JNK signaling pathway

…, YJ Xu, Y Yu, YJ Ding, WL Yu, RX Zhang, HM Zhang… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Vitexin, a flavonoids compound, is known to exhibit broad anti-oxidative, anti-inflammatory,
analgesic, and antitumor activity in many cancer xenograft models and cell lines. The …