[HTML][HTML] Irbesartan overcomes gemcitabine resistance in pancreatic cancer by suppressing stemness and iron metabolism via inhibition of the Hippo/YAP1/c-Jun axis
T Zhou, Y Xie, X Hou, W Bai, X Li, Z Liu, Q Man… - Journal of Experimental …, 2023 - Springer
Background Chemoresistance is the main reason for the poor prognosis of pancreatic ductal
adenocarcinoma (PDAC). Thus, there is an urgent need to screen out new targets and …
adenocarcinoma (PDAC). Thus, there is an urgent need to screen out new targets and …
Demoralization and depression in Chinese cancer patients
WJ Wu, M Quan, L Gao, Q Li, CX Yan, Q Zhang… - Supportive Care in …, 2021 - Springer
Objective Demoralization and depression are common in cancer patients and closely related
to suicide. But the association and difference between them are not clear. The aim of this …
to suicide. But the association and difference between them are not clear. The aim of this …
[HTML][HTML] Artificial intelligence-based comprehensive analysis of immune-stemness-tumor budding profile to predict survival of patients with pancreatic adenocarcinoma
T Zhou, Q Man, X Li, Y Xie, X Hou, H Wang… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Objective: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy. CD8+ T
cells, cancer stem cells (CSCs), and tumor budding (TB) have been significantly correlated …
cells, cancer stem cells (CSCs), and tumor budding (TB) have been significantly correlated …
[HTML][HTML] Activin A induces growth arrest through a SMAD-dependent pathway in hepatic progenitor cells
…, Q Zhou, Z Ding, H Yang, W Liu, Y Wu, Q Man… - Cell Communication and …, 2014 - Springer
Background Activin A, an important member of transforming growth factor-β superfamily, is
reported to inhibit proliferation of mature hepatocyte. However, the effect of activin A on …
reported to inhibit proliferation of mature hepatocyte. However, the effect of activin A on …
[HTML][HTML] Presence of tumor deposits is an indicator of poor prognosis in patients with pancreatic ductal adenocarcinoma
Y Liang, S Chang, H Guo, Q Man, F Zang… - American Journal of …, 2023 - ncbi.nlm.nih.gov
Tumor deposits (TDs) are associated with poor prognosis in several malignancies and have
been incorporated into the tumor-node-metastasis (TNM) staging system for colorectal …
been incorporated into the tumor-node-metastasis (TNM) staging system for colorectal …
Prognostic nutritional score based on pretreatment lymphocyte, platelet, and prealbumin predicts prognosis in patients with pancreatic cancer
Y Liang, H Guo, Q Man, S Chang… - Journal of Surgical …, 2023 - Wiley Online Library
Background and Objectives Pretreatment immunological indicators and nutritional factors
are associated with survival of many malignancies. This study aims to develop a prognostic …
are associated with survival of many malignancies. This study aims to develop a prognostic …
[PDF][PDF] A new staging system for postoperative prognostication in pancreatic ductal adenocarcinoma
Y Liang, J Cui, F Ding, Y Zou, H Guo, Q Man, S Chang… - Iscience, 2023 - cell.com
The current TNM staging system for pancreatic ductal adenocarcinoma (PDAC) has revised
the definitions of T and N categories as well as stage groups. However, studies validating …
the definitions of T and N categories as well as stage groups. However, studies validating …
[HTML][HTML] Prognostic significance of grade of malignancy based on histopathological differentiation and Ki-67 in pancreatic ductal adenocarcinoma
…, Y Zou, H Guo, Z Li, S Chang, Q Man… - Cancer Biology & …, 2024 - cancerbiomed.org
Objective: Tumor cell malignancy is indicated by histopathological differentiation and cell
proliferation. Ki-67, an indicator of cellular proliferation, has been used for tumor grading and …
proliferation. Ki-67, an indicator of cellular proliferation, has been used for tumor grading and …
[HTML][HTML] EPS15-AS1 Inhibits AKR1B1 Expression to Enhance Ferroptosis in Hepatocellular Carcinoma Cells
Q Man, G Zhang, X Chen, SR Na, S Bai, H Zhi… - Journal of …, 2024 - ncbi.nlm.nih.gov
Epidermal growth factor receptor substrate 15 (EPS15) is part of the EGFR pathway and has
been implicated in various tumorigenesis. Increasing evidence suggests that long …
been implicated in various tumorigenesis. Increasing evidence suggests that long …
[HTML][HTML] Nomogram model for predicting early recurrence for resectable pancreatic cancer: A multicenter study
Q Man, H Pang, Y Liang, S Chang, J Wang, S Gao - Medicine, 2024 - journals.lww.com
Pancreatic cancer is a highly aggressive malignancy that is characterized by early metastasis,
high recurrence, and therapy resistance. Early recurrence after surgery is one of the …
high recurrence, and therapy resistance. Early recurrence after surgery is one of the …