Glucose consumption is generally increased in tumor cells to support tumor growth. Interestingly,
we report that glycogen accumulation is a key initiating oncogenic event during liver …

Prefrontal cortex (PFC) is the cognitive center that integrates and regulates global brain
activity. However, the whole-brain organization of PFC axon projections remains poorly …

We conduct to our knowledge a first measurement study of commercial 5G performance on
smartphones by closely examining 5G networks of three carriers (two mmWave carriers, one …

Mitochondria need to be juxtaposed to phagosomes for the synergistic production of ample
reactive oxygen species (ROS) in phagocytes to kill pathogens. However, how phagosomes …

The emerging 5G services offer numerous new opportunities for networked applications. In
this study, we seek to answer two key questions: i) is the throughput of mmWave 5G …

The role of the unfolded protein response (UPR) in tissue homeostasis remains largely
unknown. Here we find that loss of Mst1/2, the mammalian Hippo orthologues, or their regulator …

Polyploidy can lead to aneuploidy and tumorigenesis. Here, we report that the Hippo pathway
effector Yap promotes the diploid-polyploid conversion and polyploid cell growth through …

The external factors that modulate Hippo signaling remain elusive. Here, we report that
FGF15 activates Hippo signaling to suppress bile acid metabolism, liver overgrowth, and …

Mapping single-neuron projections is essential for understanding brain-wide connectivity
and diverse functions of the hippocampus (HIP). Here, we reconstructed 10,100 single-neuron …

Background Abnormal androgen receptor (AR) genes can cause androgen insensitivity
syndrome (AIS), and AIS can be classified into complete androgen insensitivity syndrome (CAIS)…