User profiles for Qiangzhe Zhang

Qiangzhe Zhang

UC San Diego
Verified email at ucsd.edu
Cited by 4922

Nanoparticle-based local antimicrobial drug delivery

W Gao, Y Chen, Y Zhang, Q Zhang, L Zhang - Advanced drug delivery …, 2018 - Elsevier
Despite the wide success of antibiotics in modern medicine, the treatment of bacterial
infections still faces critical challenges, especially due to the rapid emergence of antibiotic …

Nanoparticle-hydrogel: a hybrid biomaterial system for localized drug delivery

W Gao, Y Zhang, Q Zhang, L Zhang - Annals of biomedical engineering, 2016 - Springer
Nanoparticles have offered a unique set of properties for drug delivery including high drug
loading capacity, combinatorial delivery, controlled and sustained drug release, prolonged …

White blood cell membrane‐coated nanoparticles: recent development and medical applications

…, D Bai, Q Zhang, X Ai, W Gao, L Zhang - Advanced …, 2022 - Wiley Online Library
White blood cells (WBCs) are immune cells that play essential roles in critical diseases
including cancers, infections, and inflammatory disorders. Their dynamic and diverse functions …

Nanoparticle-modified microrobots for in vivo antibiotic delivery to treat acute bacterial pneumonia

F Zhang, J Zhuang, Z Li, H Gong, BEF de Ávila… - Nature materials, 2022 - nature.com
Bioinspired microrobots capable of actively moving in biological fluids have attracted
considerable attention for biomedical applications because of their unique dynamic features that …

Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis

Q Zhang, D Dehaini, Y Zhang, J Zhou, X Chen… - Nature …, 2018 - nature.com
Rheumatoid arthritis is a common chronic inflammatory disorder and a major cause of
disability. Despite the progress made with recent clinical use of anti-cytokine biologics, the …

Modulating antibacterial immunity via bacterial membrane-coated nanoparticles

…, J Li, P Angsantikul, Q Zhang, CMJ Hu, L Zhang - Nano …, 2015 - ACS Publications
Synthetic nanoparticles coated with cellular membranes have been increasingly explored to
harness natural cell functions toward the development of novel therapeutic strategies. …

Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals

Q Zhang, J Jiang, P Han, Q Yuan, J Zhang, X Zhang… - Cell research, 2011 - nature.com
Although myocyte cell transplantation studies have suggested a promising therapeutic
potential for myocardial infarction, a major obstacle to the development of clinical therapies for …

Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management

…, Q Zhang, J Olson, BT Luk, S Zhang… - Proceedings of the …, 2017 - National Acad Sciences
Sepsis, resulting from uncontrolled inflammatory responses to bacterial infections, continues
to cause high morbidity and mortality worldwide. Currently, effective sepsis treatments are …

Cellular nanosponges inhibit SARS-CoV-2 infectivity

Q Zhang, A Honko, J Zhou, H Gong, SN Downs… - Nano …, 2020 - ACS Publications
We report cellular nanosponges as an effective medical countermeasure to the SARS-CoV-2
virus. Two types of cellular nanosponges are made of the plasma membranes derived from …

Targeted gene silencing in vivo by platelet membrane–coated metal-organic framework nanoparticles

…, J Zhou, Q Zhang, W Gao, RH Fang, L Zhang - Science …, 2020 - science.org
Small interfering RNA (siRNA) is a powerful tool for gene silencing that has been used for a
wide range of biomedical applications, but there are many challenges facing its therapeutic …