User profiles for Qiangzhe Zhang
Qiangzhe ZhangUC San Diego Verified email at ucsd.edu Cited by 4922 |
Nanoparticle-based local antimicrobial drug delivery
Despite the wide success of antibiotics in modern medicine, the treatment of bacterial
infections still faces critical challenges, especially due to the rapid emergence of antibiotic …
infections still faces critical challenges, especially due to the rapid emergence of antibiotic …
Nanoparticle-hydrogel: a hybrid biomaterial system for localized drug delivery
Nanoparticles have offered a unique set of properties for drug delivery including high drug
loading capacity, combinatorial delivery, controlled and sustained drug release, prolonged …
loading capacity, combinatorial delivery, controlled and sustained drug release, prolonged …
White blood cell membrane‐coated nanoparticles: recent development and medical applications
White blood cells (WBCs) are immune cells that play essential roles in critical diseases
including cancers, infections, and inflammatory disorders. Their dynamic and diverse functions …
including cancers, infections, and inflammatory disorders. Their dynamic and diverse functions …
Nanoparticle-modified microrobots for in vivo antibiotic delivery to treat acute bacterial pneumonia
Bioinspired microrobots capable of actively moving in biological fluids have attracted
considerable attention for biomedical applications because of their unique dynamic features that …
considerable attention for biomedical applications because of their unique dynamic features that …
Neutrophil membrane-coated nanoparticles inhibit synovial inflammation and alleviate joint damage in inflammatory arthritis
Rheumatoid arthritis is a common chronic inflammatory disorder and a major cause of
disability. Despite the progress made with recent clinical use of anti-cytokine biologics, the …
disability. Despite the progress made with recent clinical use of anti-cytokine biologics, the …
Modulating antibacterial immunity via bacterial membrane-coated nanoparticles
Synthetic nanoparticles coated with cellular membranes have been increasingly explored to
harness natural cell functions toward the development of novel therapeutic strategies. …
harness natural cell functions toward the development of novel therapeutic strategies. …
Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals
Although myocyte cell transplantation studies have suggested a promising therapeutic
potential for myocardial infarction, a major obstacle to the development of clinical therapies for …
potential for myocardial infarction, a major obstacle to the development of clinical therapies for …
Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management
Sepsis, resulting from uncontrolled inflammatory responses to bacterial infections, continues
to cause high morbidity and mortality worldwide. Currently, effective sepsis treatments are …
to cause high morbidity and mortality worldwide. Currently, effective sepsis treatments are …
Cellular nanosponges inhibit SARS-CoV-2 infectivity
We report cellular nanosponges as an effective medical countermeasure to the SARS-CoV-2
virus. Two types of cellular nanosponges are made of the plasma membranes derived from …
virus. Two types of cellular nanosponges are made of the plasma membranes derived from …
Targeted gene silencing in vivo by platelet membrane–coated metal-organic framework nanoparticles
Small interfering RNA (siRNA) is a powerful tool for gene silencing that has been used for a
wide range of biomedical applications, but there are many challenges facing its therapeutic …
wide range of biomedical applications, but there are many challenges facing its therapeutic …