Metabolic reprogramming is an emerging hallmark of cancer cells, in which cancer cells
exhibit distinct metabolic phenotypes to fuel their proliferation and progression. The significant …

Breast cancer (BC) is the most common malignant tumor among women, with high morbidity
and mortality. Its onset, development, metastasis, and prognosis vary among individuals …

Proton-coupled monocarboxylate transporters (MCTs), representing the first four isoforms of
the SLC16A gene family, mainly participate in the transport of lactate, pyruvate, and other …

Background: Hypoxia is a hallmark of the physical microenvironment of solid tumors. As a
key factor that regulates tumor development and progression, hypoxia can reprogram the …

Triple-negative breast cancer (TNBC) is a heterogeneous breast cancer subtype and accounts
for approximately 15–20% of breast cancer cases. In this study, we identified KLHL29, …

Obesity is a well-known modifiable risk factor for breast cancer and is considered a poor
prognostic factor in pre-and post-menopausal women. While the systemic effects of obesity …

Metastasis and drug resistance are the leading causes of death for breast cancer patients.
Epithelial–mesenchymal transition (EMT), a transition from polarized epithelial cells to motile …

Currently, neoadjuvant chemotherapy is a standard therapeutic strategy for breast cancer,
as it can provide timely and individualized chemo-sensitivity information and is beneficial for …

… metastasis by influencing leukemia inhibitory factor receptor - Wang - 2018 - Cancer Science
- Wiley Online Library … Mozhi Wang and Mengshen Wang contributed equally to this work. …

Objective: Neoadjuvant therapy (NAT) has been widely implemented as an essential treatment
to improve therapeutic efficacy in patients with locally-advanced cancer to reduce tumor …