[HTML][HTML] Cancer immunotherapy based on natural killer cells: current progress and new opportunities

W Hu, G Wang, D Huang, M Sui, Y Xu - Frontiers in immunology, 2019 - frontiersin.org
Cancer immunotherapy has been firmly established as a new milestone for cancer therapy,
with the development of multiple immune cells as therapeutic tools. Natural killer (NK) cells …

Nanoparticles for tumor targeted therapies and their pharmacokinetics

J Wang, M Sui, W Fan - Current drug metabolism, 2010 - ingentaconnect.com
Various types of nanoparticles, such as liposomes, polymeric micelles, dendrimers,
superparamagnetic iron oxide crystals, and colloidal gold, have been employed in targeted …

Targeting arginine metabolism pathway to treat arginine-dependent cancers

F Qiu, J Huang, M Sui - Cancer letters, 2015 - Elsevier
The significant disparities in metabolism between tumor and normal cells have inspired the
development of metabolism-based anti-tumor therapeutics. Arginine is a semi-essential …

Prodrugs forming high drug loading multifunctional nanocapsules for intracellular cancer drug delivery

Y Shen, E Jin, B Zhang, CJ Murphy, M Sui… - Journal of the …, 2010 - ACS Publications
Anticancer drugs embedded in or conjugated with inert nanocarriers, referred to as
nanomedicines, show many therapeutic advantages over free drugs, but the inert carrier materials …

The role of micelle size in tumor accumulation, penetration, and treatment

J Wang, W Mao, LL Lock, J Tang, M Sui, W Sun… - ACS …, 2015 - ACS Publications
The specific sizes that determine optimal nanoparticle tumor accumulation, penetration, and
treatment remain inconclusive because many studies compared nanoparticles with multiple …

Tumor redox heterogeneity‐responsive prodrug nanocapsules for cancer chemotherapy

…, X Sun, W Mao, W Sun, J Tang, M Sui… - Advanced …, 2013 - Wiley Online Library
Nanocarriers have been extensively explored for cancer drug delivery to increase the solubility
of the drug in water [1] and tumor accumulation [2] by means of its enhanced permeation …

Linear-dendritic drug conjugates forming long-circulating nanorods for cancer-drug delivery

Z Zhou, X Ma, E Jin, J Tang, M Sui, Y Shen… - Biomaterials, 2013 - Elsevier
Elongated micelles have many desirable characteristics for cancer-drug delivery, but they
are difficult to obtain since amphiphilic polymers form such nanostructures only within narrow …

Nuclear drug delivery for cancer chemotherapy

M Sui, W Liu, Y Shen - Journal of controlled release, 2011 - Elsevier
Nanosystems with unique physical and biological properties have been extensively explored
for cancer targeted intracellular delivery of small-molecular chemotherapeutic drugs to …

Conjugate of Pt (IV)–histone deacetylase inhibitor as a prodrug for cancer chemotherapy

J Yang, X Sun, W Mao, M Sui, J Tang… - Molecular …, 2012 - ACS Publications
Platinum(IV) prodrug diaminedichlorodihydroxyplatinum (ACHP) conjugated with a histone
deacetylase (HDAC) inhibitor valproic acid (VA), VAAP, exhibited strong synergistic …

Amphiphilic curcumin conjugate-forming nanoparticles as anticancer prodrug and drug carriers: in vitro and in vivo effects

H Tang, CJ Murphy, B Zhang, Y Shen, M Sui… - …, 2010 - Future Medicine
Curcumin has been shown to have high cytotoxicity towards various cancer cell lines, but its
water insolubility and instability make its bioavailability exceedingly low and, thus, it is …