User profiles for Mehrdad Asghari Estiar

Mehrdad Asghari Estiar

Broad Institute of MIT and Harvard
Verified email at broadinstitute.org
Cited by 1430

Carbon nanotubes part II: a remarkable carrier for drug and gene delivery

M Karimi, N Solati, A Ghasemi, MA Estiar… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: Carbon nanotubes (CNT) have recently been studied as novel and versatile
drug and gene delivery vehicles. When CNT are suitably functionalized, they can interact with …

Carbon nanotubes part I: preparation of a novel and versatile drug-delivery vehicle

…, M Hashemkhani, A Saeidi, MA Estiar… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: It is 23 years since carbon allotrope known as carbon nanotubes (CNT) was
discovered by Iijima, who described them as “rolled graphite sheets inserted into each other”. …

[HTML][HTML] ATM in breast and brain tumors: a comprehensive review

MA Estiar, P Mehdipour - Cancer biology & medicine, 2018 - ncbi.nlm.nih.gov
The ATM gene is mutated in the syndrome, ataxia-telangiectasia (AT), which is characterized
by predisposition to cancer. Patients with AT have an elevated risk of breast and brain …

Effects of zinc supplementation on antioxidant status and lipid peroxidation in hemodialysis patients

…, A Ghorbanihaghjo, A Hamdi, MA Estiar… - Journal of Renal …, 2013 - Elsevier
OBJECTIVES: This study was designed to determine the effects of zinc supplementation on
oxidative stress in hemodialysis (HD) patients through evaluating total antioxidant capacity (…

[HTML][HTML] Methylenetetrahydrofolate reductase C677T and A1298C mutations in women with recurrent spontaneous abortions in the Northwest of Iran

…, N Chaparzadeh, M Asghari Estiar… - International Scholarly …, 2012 - hindawi.com
Introduction. Recurrent spontaneous abortion (RSA) is a significant obstetrical complication
that may occur during pregnancy. Various studies in recent years have indicated that two …

[PDF][PDF] siRNA-mediated silencing of survivin inhibits proliferation and enhances etoposide chemosensitivity in acute myeloid leukemia cells

H Karami, B Baradaran, A Esfahani, MA Estiar… - Asian Pacific Journal of …, 2013 - Citeseer
Background: Overexpression of survivin, a known inhibitor of apoptosis, is associated with
tumor progression and drug resistance in numerous malignancies, including leukemias. The …

[HTML][HTML] Deregulated expression of HDAC3 in colorectal cancer and its clinical significance

M Nemati, N Ajami, MA Estiar… - … in Clinical and …, 2018 - advances.umw.edu.pl
Background. To date, 4 classes of histone deacetylases (HDACs) have been identified in
humans. Class I HDACs are zinc-dependent and NAD+-independent enzymes, and include 4 …

[PDF][PDF] Expression analysis of aurora-C and Survivin, two testis-specific genes, in patients with colorectal cancer

S Hosseini, S Hashemzadeh, MA Estiar… - Clin Lab, 2015 - researchgate.net
Background: Colorectal cancer (CRC) is one of the leading causes of cancer-related death
worldwide. The high frequency of positive families shows the importance of public awareness …

[HTML][HTML] Detection of aberrant methylated SEPT9 and NTRK3 genes in sporadic colorectal cancer patients as a potential diagnostic biomarker

…, M Ghojazadeh, AH Mehrtash, MA Estiar… - Oncology …, 2016 - spandidos-publications.com
Colorectal cancer (CRC) is one of the most common malignancies, and the third leading
cause of cancer mortality worldwide. Timely detection of CRC in patients with earlier stages …

[HTML][HTML] HER2 gene amplification in patients with prostate cancer: Evaluating a CISH-based method

…, M Khaleghiyan, MA Estiar… - Oncology …, 2016 - spandidos-publications.com
Prostate cancer (PCa) is one of the most widespread malignancies in the world. The role of
the human epidermal growth factor receptor 2 (HER2) in the pathogenesis and progression …