The present study aimed to analyze the expression profile of the microRNAs previously
described as associated with childhood ALL, miR-92a, miR-100, miR-125a-5p, miR-128a, miR-…

Glioblastoma is the most frequent and malignant brain tumor, characterized by an elevated
capacity for cellular proliferation and invasion. Recently, it was demonstrated that podoplanin …

Propolis is a resin formed by a complex chemical composition of substances that bees
collect from plants. Since ancient times, propolis has been used in folk medicine, due to its …

Acute lymphoblastic leukemia (ALL) is the most common type of pediatric neoplasia. Highly
heterogeneous, ALL includes several genetic subtypes with varying clinical outcome. …

Background aims. Mesenchymal stromal cells (MSC) are being used to treat and prevent a
variety of clinical conditions. To be readily available, MSC must be cryopreserved until …

Cancer targeted therapy, either alone or in combination with conventional chemotherapy,
could allow the survival of patients with neoplasms currently considered incurable. In recent …

For decades, cancer biology focused largely on the protein-encoding genes that have clear
roles in tumor development or progression: cell-cycle control, apoptotic evasion, genome …

Despite efforts to improve surgical, radiologic, and chemotherapeutic strategies, the outcome
of patients with glioblastoma (GBM) is still poor. Polo-like kinase 1 (PLK1) is a serine/…

Background Glioblastoma is the most common tumor of the central nervous system and one
of the hardest tumors to treat. Consequently, the search for novel therapeutic options is …

Musashi comprises an evolutionarily conserved family of RNA‐binding proteins (RBP) that
regulate cell fate decisions during embryonic development and play key roles in the …