User profiles for Kai Wang

Kai Wang

- Verified email at email.chop.edu - Cited by 57480

Kai Wang

- Verified email at systemsbiology.org - Cited by 22083

Kevin I-Kai Wang

- Verified email at auckland.ac.nz - Cited by 5892

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

K Wang, M Li, H Hakonarson - Nucleic acids research, 2010 - academic.oup.com
High-throughput sequencing platforms are generating massive amounts of genetic variation
data for diverse genomes, but it remains a challenge to pinpoint a small subset of …

Facile Synthesis of Graphene Nanosheets via Fe Reduction of Exfoliated Graphite Oxide

ZJ Fan, W Kai, J Yan, T Wei, LJ Zhi, J Feng, Y Ren… - ACS …, 2011 - ACS Publications
The synthesis of graphene nanosheets from graphite oxide typically involves harmful
chemical reductants that are undesirable for most practical applications of graphene. Here, we …

Analysing biological pathways in genome-wide association studies

K Wang, M Li, H Hakonarson - Nature Reviews Genetics, 2010 - nature.com
Genome-wide association (GWA) studies have typically focused on the analysis of single
markers, which often lacks the power to uncover the relatively small effect sizes conferred by …

Durvalumab plus platinum–etoposide versus platinum–etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled …

…, Z Lin, R Ma, S Ma, K Nan, Y Shu, K Wang, M Wang… - The Lancet, 2019 - thelancet.com
Background Most patients with small-cell lung cancer (SCLC) have extensive-stage disease
at presentation, and prognosis remains poor. Recently, immunotherapy has demonstrated …

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

A Franke, DPB McGovern, JC Barrett, K Wang… - Nature …, 2010 - nature.com
We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS)
comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the …

PennCNV: an integrated hidden Markov model designed for high-resolution copy number variation detection in whole-genome SNP genotyping data

K Wang, M Li, D Hadley, R Liu, J Glessner… - Genome …, 2007 - genome.cshlp.org
Comprehensive identification and cataloging of copy number variations (CNVs) is required
to provide a complete view of human genetic variation. The resolution of CNV detection in …

Photoinduced Polymerization of Solid C60 Films

…, P Zhou, KA Wang, GT Hager, JM Holden, Y Wang… - Science, 1993 - science.org
The irradiation of oxygen-free, face-centered-cubic C 60 films with visible or ultraviolet light
phototransformed C 60 into a different solid phase. Results from laser desorption mass …

Digital Twin-driven smart manufacturing: Connotation, reference model, applications and research issues

Y Lu, C Liu, I Kevin, K Wang, H Huang, X Xu - Robotics and computer …, 2020 - Elsevier
This paper reviews the recent development of Digital Twin technologies in manufacturing
systems and processes, to analyze the connotation, application scenarios, and research …

Circular RNAs are abundant, conserved, and associated with ALU repeats

WR Jeck, JA Sorrentino, K Wang, MK Slevin, CE Burd… - Rna, 2013 - rnajournal.cshlp.org
Circular RNAs composed of exonic sequence have been described in a small number of
genes. Thought to result from splicing errors, circular RNA species possess no known function. …

Hierarchical nanocomposites of polyaniline nanowire arrays on graphene oxide sheets with synergistic effect for energy storage

J Xu, K Wang, SZ Zu, BH Han, Z Wei - ACS nano, 2010 - ACS Publications
We introduced a facile method to construct hierarchical nanocomposites by combining one-dimensional
(1D) conducting polyaniline (PANI) nanowires with 2D graphene oxide (GO) …