Multidrug resistance (MDR) is the phenomenon in which cancer cells simultaneously develop
resistance to a broad spectrum of structurally and mechanistically unrelated drugs. MDR …

FBXW7 (F-Box and WD Repeat Domain Containing 7) (also referred to as FBW7 or hCDC4)
is a component of the Skp1-Cdc53 / Cullin-F-box-protein complex (SCF/β-TrCP). As a …

Vaccines are one of the most significant medical interventions in the fight against infectious
diseases. Since their discovery by Edward Jenner in 1796, vaccines have reduced the …

Animals move over a range of speeds by using rhythmic networks of neurons located in the
spinal cord 1 , 2 , 3 , 4 , 5 , 6 . Here we use electrophysiology and in vivo imaging in larval …

Rationale: Both genetic and environmental factors contribute to lung cancer, but the degree
to which air pollution modifies the impact of genetic susceptibility on lung cancer remains …

The study aims to explore the risk of depression in left-behind children in grades four–six in
rural China and to identify the factors associated with increased depression risk in this …

Background Genetic variation has an important role in the development of non-small-cell
lung cancer (NSCLC). However, genetic factors for lung cancer have not been fully identified, …

Objectives To investigate rates of depression and suicidal ideation in medical students in
mainland China and to explore wellness curricula and mental health services available to …

NLRP3 inflammasome was introduced as a double-edged sword in tumorigenesis and
influenced immunotherapy response by modulating host immunity. However, a systematic …

We present the largest whole-genome sequencing (WGS) study of non-small cell lung
cancer (NSCLC) to date among 6,004 individuals of Chinese ancestry, coupled with 23,049 …