Irbesartan overcomes gemcitabine resistance in pancreatic cancer by suppressing stemness and iron metabolism via inhibition of the Hippo/YAP1/c-Jun axis
…, W Bai, X Li, Z Liu, Q Man, J Sun, D Fu, J Yan… - Journal of Experimental …, 2023 - Springer
Background Chemoresistance is the main reason for the poor prognosis of pancreatic ductal
adenocarcinoma (PDAC). Thus, there is an urgent need to screen out new targets and …
adenocarcinoma (PDAC). Thus, there is an urgent need to screen out new targets and …
[HTML][HTML] Artificial intelligence-based comprehensive analysis of immune-stemness-tumor budding profile to predict survival of patients with pancreatic adenocarcinoma
…, Q Man, X Li, Y Xie, X Hou, H Wang, J Yan… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Objective: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy. CD8+ T
cells, cancer stem cells (CSCs), and tumor budding (TB) have been significantly correlated …
cells, cancer stem cells (CSCs), and tumor budding (TB) have been significantly correlated …
[HTML][HTML] Nuclear PLD1 combined with NPM1 induces gemcitabine resistance through tumorigenic IL7R in pancreatic adenocarcinoma
D Fu, J Yan, Z Zhang, Y Liu, X Ma, J Ding… - Cancer Biology & …, 2023 - ncbi.nlm.nih.gov
Objective: Pancreatic ductal adenocarcinoma (PDAC) is a highly malignant gastrointestinal
cancer with a 5-year survival rate of only 9%. Of PDAC patients, 15%-20% are eligible for …
cancer with a 5-year survival rate of only 9%. Of PDAC patients, 15%-20% are eligible for …
SDCBP promotes pancreatic cancer progression by preventing YAP1 from β-TrCP-mediated proteasomal degradation
…, J Sun, Y Wang, X Li, X Hou, Z Liu, D Fu, J Yan… - Gut, 2023 - gut.bmj.com
Objective Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal tumour with limited
treatment options. Here, we identified syndecan binding protein (SDCBP), also known as …
treatment options. Here, we identified syndecan binding protein (SDCBP), also known as …
Silencing Sly-miR167a delayed preharvest ripening of tomato fruit
W Duan, J Yan, L Li, H Song, L Meng, Z Zhang… - Postharvest Biology and …, 2024 - Elsevier
The miRNA167 (miR167a) family is a conserved type of microRNA in plants, which mainly
regulates the Auxin Response Factors (ARF) family genes to influence the auxin signaling …
regulates the Auxin Response Factors (ARF) family genes to influence the auxin signaling …
Triple‐negative breast cancer survival prediction using artificial intelligence through integrated analysis of tertiary lymphoid structures and tumor budding
…, Y Xie, T Zhou, T Xue, X Qian, J Li, HC Wang, J Yan… - Cancer, 2024 - Wiley Online Library
Background Triple‐negative breast cancer (TNBC) is a highly heterogeneous and clinically
aggressive disease. Accumulating evidence indicates that tertiary lymphoid structures (TLSs) …
aggressive disease. Accumulating evidence indicates that tertiary lymphoid structures (TLSs) …
Crossed cerebellar diaschisis after acute ischemic stroke detected by intravoxel incoherent motion magnetic resonance imaging
…, L Zhao, K Yuan, J Yan, Y Zhang, J Zhu, C Yan - Neurological …, 2022 - Springer
Purpose To study the value of 3.0 T magnetic resonance imaging with intravoxel incoherent
motion (IVIM) in the diagnosis of the crossed cerebellar diaschisis (CCD) after the unilateral …
motion (IVIM) in the diagnosis of the crossed cerebellar diaschisis (CCD) after the unilateral …
Microwave ablation versus laparoscopic resection for hepatocellular carcinoma in patients with clinically significant portal hypertension: a propensity score–matched …
H Yu, F Zhao, X Men, H Zhu, J Yan, Z Liu, Q Liu… - European …, 2023 - Springer
Objectives The study of postoperative liver decompensation after microwave ablation (MWA)
for hepatocellular carcinoma (HCC) in patients with clinically significant portal hypertension …
for hepatocellular carcinoma (HCC) in patients with clinically significant portal hypertension …
Realization path of social capital “exit from virtual to real”: evidence from China
S Xu, X Wan, Y Li, J Yan - Kybernetes, 2022 - emerald.com
Purpose How to realize social capital “exit from virtual to real” has become not only a hot issue
that elicited economists' and the practice field's concern but also a key economic structure …
that elicited economists' and the practice field's concern but also a key economic structure …
A cohort autopsy study defines COVID-19 systemic pathogenesis
Severe COVID-19 disease caused by SARS-CoV-2 is frequently accompanied by dysfunction
of the lungs and extrapulmonary organs. However, the organotropism of SARS-CoV-2 and …
of the lungs and extrapulmonary organs. However, the organotropism of SARS-CoV-2 and …