[PDF][PDF] Molecular evolution of early-onset prostate cancer identifies molecular risk markers and clinical trajectories

…, GH Henry, TN Yamaguchi, A Malewska, J Meiners… - Cancer cell, 2018 - cell.com
Identifying the earliest somatic changes in prostate cancer can give important insights into
tumor evolution and aids in stratifying high- from low-risk disease. We integrated whole …

Results of total hip replacement using the Robodoc surgical assistant system: clinical outcome and evaluation of complications for 97 procedures

…, C Queitsch, A Von Haugwitz, J Meiners… - … Journal of Medical …, 2007 - Wiley Online Library
Background A computerized robotic surgical system was developed from 1986 by the
Thomas J. Watson Research Center. In 1992 the system unit Orthodoc ® and the milling robot …

[PDF][PDF] Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

…, A Duprée, P Scognamiglio, G Plitzko, J Meiners… - Immunity, 2023 - cell.com
During metastasis, cancer cells invade, intravasate, enter the circulation, extravasate, and
colonize target organs. Here, we examined the role of interleukin (IL)-22 in metastasis. …

[HTML][HTML] Random forest-based modelling to detect biomarkers for prostate cancer progression

…, G Sauter, C Plass, Y Assenov, R Simon, J Meiners… - Clinical …, 2019 - Springer
Background The clinical course of prostate cancer (PCa) is highly variable, demanding an
individualized approach to therapy. Overtreatment of indolent PCa cases, which likely do not …

[HTML][HTML] IL22BP mediates the antitumor effects of lymphotoxin against colorectal tumors in mice and humans

…, PC Arck, A Stein, R Simon, A Daubmann, J Meiners… - Gastroenterology, 2020 - Elsevier
Background & Aims Unregulated activity of interleukin (IL) 22 promotes intestinal tumorigenesis
in mice. IL22 binds the antagonist IL22 subunit alpha 2 (IL22RA2, also called IL22BP). …

[HTML][HTML] Up-regulation of lysophosphatidylcholine acyltransferase 1 (LPCAT1) is linked to poor prognosis in breast cancer

P Lebok, A von Hassel, J Meiners… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Dysregulation of lipid metabolism is common in cancer. Lysophosphatidylcholine acyltransferase
1 (LPCAT1) has been implicated with various cancer types. Here we analyzed by …

[HTML][HTML] Prognostic value of preoperative circulating tumor cells counts in patients with UICC stage I-IV colorectal cancer

TSA Abdalla, J Meiners, S Riethdorf, A König… - PLoS …, 2021 - journals.plos.org
Colorectal cancer (CRC) is one of the leading causes of cancer death worldwide. There is
an urgent need to identify prognostic markers for patients undergoing curative resection of …

Electrocardiographic changes during therapeutic hypothermia

P Lebiedz, J Meiners, A Samol, K Wasmer, H Reinecke… - Resuscitation, 2012 - Elsevier
AIMS: Induced mild therapeutic hypothermia (MTH) is an effective treatment to improve
outcome after out-of-hospital resuscitation. Adverse events are rare, but arrhythmias and …

[HTML][HTML] PITX1 is a regulator of TERT expression in prostate cancer with prognostic power

…, N Jaishankar, D Röll, M Oswald, J Meiners… - Cancers, 2022 - mdpi.com
Simple Summary Most prostate cancer is of an indolent form and is curable. However, some
prostate cancer belongs to rather aggressive subtypes leading to metastasis and death, and …

Hyperparameter optimization for image analysis: application to prostate tissue images and live cell data of virus-infected cells

…, M Gunkel, DM Braun, JY Lee, J Meiners… - International journal of …, 2019 - Springer
Purpose Automated analysis of microscopy image data typically requires complex pipelines
that involve multiple methods for different image analysis tasks. To achieve best results of …