Tumor neoantigen is the truly foreign protein and entirely absent from normal human organs/tissues.
It could be specifically recognized by neoantigen-specific T cell receptors (TCRs) in …

Background PD-L1 expression on neutrophils contributes to the impaired immune response
in infectious disease, but the detailed role of PD-L1 expression on neutrophils in HCC …

Background Tumor mutational burden (TMB) is a significant predictor of immune checkpoint
inhibitors (ICIs) efficacy. This study investigated the correlation between deep learning …

As the coronavirus 2019 (COVID-19) continues to spread globally, hundreds of thousands
have been infected, among whom approximately 15% of COVID-19 patients develop severe …

Background & Aims S100A4 has been linked to the fibrosis of several organs due to its role
as a fibroblast-specific marker. However, the role of S100A4 itself in the development of …

Bladder cancer is one of the most common malignancies in the world. Cisplatin is one of the
most potent and widely used anticancer drugs and has been employed in several …

Introduction To depict the genomic landscape of Chinese early-stage lung squamous cell
carcinoma (LUSC) and investigate its correlation with tumor mutation burden (TMB), PD-L1 …

Background: The genomic spectrum of biliary tract carcinoma (BTC) has been characterized
and is associated with distinct anatomic and etiologic subtypes, yet limited studies have …

Tea (Camellia sinensis, Theaceae) is one of the most widely consumed beverages in the
world. The three major types of tea, green tea, oolong tea, and black tea, differ in terms of the …

Background Despite the great achievements made in immune-checkpoint-blockade (ICB) in
cancer therapy, there are no effective predictive biomarkers in gastrointestinal (GI) cancer. …