Checkpoint blockade enhances effector T cell function and has elicited long-term remission
in a subset of patients with a broad spectrum of cancers. TIGIT is a checkpoint receptor …

Human natural killer ( NK ) cells have distinct functions as NK tolerant , NK cytotoxic and NK
regulatory cells and can be divided into different subsets based on the relative expression of …

Natural killer (NK) cells are effective in combating infections and tumors and as such are
tempting for adoptive transfer therapy. However, they are not homogeneous but can be divided …

Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV (SARS-CoV)
and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …

After analyzing the immune characteristics of patients with severe coronavirus disease 2019
(COVID-19), we have identified that pathogenic T cells and inflammatory monocytes with …

Pathogenic human coronavirus infections, such as severe acute respiratory syndrome CoV (SARS-CoV)
and Middle East respiratory syndrome CoV (MERS-CoV), cause high morbidity …

Several studies show that the immunosuppressive drugs targeting the interleukin-6 (IL-6)
receptor, including tocilizumab, ameliorate lethal inflammatory responses in COVID-19 patients …

During pregnancy, the maternal uterus and fetus form a special microenvironment at the
maternal-fetal interface to support fetal development. Extravillous trophoblasts (EVTs), …

For predominant abundance with liver-specific Kupffer cells, natural killer (NK) cells, and
natural killer T (NKT) cells and their rapid responses to several stimuli, the liver is considered as …

Pregnancy is a unique type of immunological process. Healthy pregnancy is associated
with a series of inflammatory events: implantation (inflammation), gestation (anti-inflammation), …