User profiles for Guowang Xu

Guowang Xu

Dalian Institute of Chemical Physics, Chinese Academy of Sciences
Verified email at dicp.ac.cn
Cited by 31095

Mass spectrometry-based metabolomics: a guide for annotation, quantification and best reporting practices

…, H Tang, T Tohge, Y Wang, W Wen, S Wu, G Xu… - Nature …, 2021 - nature.com
Mass spectrometry-based metabolomics approaches can enable detection and
quantification of many thousands of metabolite features simultaneously. However, compound …

Effects of pre-analytical processes on blood samples used in metabolomics studies

P Yin, R Lehmann, G Xu - Analytical and bioanalytical chemistry, 2015 - Springer
Every day, analytical and bio-analytical chemists make sustained efforts to improve the
sensitivity, specificity, robustness, and reproducibility of their methods. Especially in targeted and …

Gut microbiome and serum metabolome alterations in obesity and after weight-loss intervention

…, W Gu, X Deng, B Shen, X Xu, H Yang, G Xu… - Nature medicine, 2017 - nature.com
Emerging evidence has linked the gut microbiome to human obesity. We performed a
metagenome-wide association study and serum metabolomics profiling in a cohort of lean and …

Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry for metabonomics: Biomarker discovery for diabetes mellitus

…, Z Xu, X Lu, X Yang, P Yin, H Kong, Y Yu, G Xu - Analytica Chimica Acta, 2009 - Elsevier
Comprehensive two-dimensional gas chromatography/time-of-flight mass spectrometry (GC×GC–TOFMS)
coupled with pattern recognition methods was applied to analyze plasma from …

Analytical strategies in lipidomics and applications in disease biomarker discovery

…, M Wang, J van der Greef, T Hankemeier, G Xu - … of Chromatography B, 2009 - Elsevier
Lipidomics is a lipid-targeted metabolomics approach aiming at comprehensive analysis of
lipids in biological systems. Recently, lipid profiling, or so-called lipidomics research, has …

A comparative study of volatile components in green, oolong and black teas by using comprehensive two-dimensional gas chromatography–time-of-flight mass …

L Zhang, Z Zeng, C Zhao, H Kong, X Lu, G Xu - Journal of Chromatography …, 2013 - Elsevier
The difference of volatile components in green, oolong and black teas was studied by using
comprehensive two-dimensional gas chromatography–time-of-flight mass spectrometry (GC …

Altered lipid metabolism in recovered SARS patients twelve years after infection

Q Wu, L Zhou, X Sun, Z Yan, C Hu, J Wu, L Xu, X Li… - Scientific reports, 2017 - nature.com
Severe acute respiratory syndrome-coronavirus (SARS-CoV) and SARS-like coronavirus
are a potential threat to global health. However, reviews of the long-term effects of clinical …

Metabolic characterization of hepatocellular carcinoma using nontargeted tissue metabolomics

…, Y Tan, P Yin, G Ye, P Gao, X Lu, H Wang, G Xu - Cancer research, 2013 - AACR
Hepatocellular carcinoma has a poor prognosis due to its rapid development and early
metastasis. In this report, we characterized the metabolic features of hepatocellular carcinoma …

Gut microbiome-related effects of berberine and probiotics on type 2 diabetes (the PREMOTE study)

…, Z Shi, X Li, Y Qiu, Y Zou, H Yang, J Wang, G Xu… - Nature …, 2020 - nature.com
Human gut microbiome is a promising target for managing type 2 diabetes (T2D). Measures
altering gut microbiota like oral intake of probiotics or berberine (BBR), a bacteriostatic agent…

Plasma phospholipid metabolic profiling and biomarkers of type 2 diabetes mellitus based on high-performance liquid chromatography/electrospray mass …

…, H Kong, Y Guan, J Yang, J Gu, S Yang, G Xu - Analytical …, 2005 - ACS Publications
Liquid chromatography/mass spectrometry (LC/MS) followed by multivariate statistical analysis
has been successfully applied to the plasma phospholipids metabolic profiling in type 2 …