[HTML][HTML] Remdesivir in adults with severe COVID-19: a randomised, double-blind, placebo-controlled, multicentre trial
Y Wang, D Zhang, G Du, R Du, J Zhao, Y Jin, S Fu… - The lancet, 2020 - thelancet.com
Background No specific antiviral drug has been proven effective for treatment of patients
with severe coronavirus disease 2019 (COVID-19). Remdesivir (GS-5734), a nucleoside …
with severe coronavirus disease 2019 (COVID-19). Remdesivir (GS-5734), a nucleoside …
Astragaloside IV derived from Astragalus membranaceus: A research review on the pharmacological effects
J Zhang, C Wu, L Gao, G Du, X Qin - Advances in Pharmacology, 2020 - Elsevier
Decoctions prepared from the roots of Astragali Radix are known as “Huangqi” and are
widely used in traditional Chinese medicine for treatment of viral and bacterial infections, …
widely used in traditional Chinese medicine for treatment of viral and bacterial infections, …
[HTML][HTML] The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro
…, Q Lv, F Li, H Liu, B Hou, X Peng, Y Lu, G Du - Biochemical …, 2021 - Elsevier
Baicalein is the main active compound of Scutellaria baicalensis Georgi, a medicinal herb
with multiple pharmacological activities, including the broad anti-virus effects. In this paper, …
with multiple pharmacological activities, including the broad anti-virus effects. In this paper, …
Neuroprotective effect of baicalein against MPTP neurotoxicity: behavioral, biochemical and immunohistochemical profile
…, G He, X Mu, T Zhang, X Li, J Hu, B Xu, G Du - Neuroscience …, 2008 - Elsevier
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) causes the damage of dopaminergic
neurons as seen in Parkinson's disease (PD). Oxidative stress has been implicated in the …
neurons as seen in Parkinson's disease (PD). Oxidative stress has been implicated in the …
Skeletal muscle atrophy: From mechanisms to treatments
…, N Li, W Jia, N Wang, M Liang, X Yang, G Du - Pharmacological …, 2021 - Elsevier
Skeletal muscle is a crucial tissue for movement, gestural assistance, metabolic homeostasis,
and thermogenesis. It makes up approximately 40% of the total body weight and 50% of …
and thermogenesis. It makes up approximately 40% of the total body weight and 50% of …
[HTML][HTML] The biology, function, and applications of exosomes in cancer
…, X Zheng, Y Yang, W Fu, J Yi, J Wang, G Du - … Pharmaceutica Sinica B, 2021 - Elsevier
Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids, proteins…
fusion of multivesicular bodies with the cell surface. They can transport nucleic acids, proteins…
Baicalein exerts neuroprotective effects in 6-hydroxydopamine-induced experimental parkinsonism in vivo and in vitro
X Mu, G He, Y Cheng, X Li, B Xu, G Du - Pharmacology Biochemistry and …, 2009 - Elsevier
Baicalein, a flavonoid obtained from the root of Chinese medicinal herb Scutellaria baicalensis,
has been shown to exert a protective effect on neurons against several neuronal insults. …
has been shown to exert a protective effect on neurons against several neuronal insults. …
The strategies and techniques of drug discovery from natural products
…, T Yuan, W Li, W Zhang, B Hou, Y Lu, G Du - Pharmacology & …, 2020 - Elsevier
Natural products have been the main sources of new drugs. The different strategies have
been developed to find the new drugs based on natural products. The traditional and ethic …
been developed to find the new drugs based on natural products. The traditional and ethic …
In vitro anti-influenza virus and anti-inflammatory activities of theaflavin derivatives
M Zu, F Yang, W Zhou, A Liu, G Du, L Zheng - Antiviral research, 2012 - Elsevier
The theaflavins fraction (TF80%, with a purity of 80%) and three theaflavin (TF) derivatives
from black tea have been found to exhibit potent inhibitory effects against influenza virus in …
from black tea have been found to exhibit potent inhibitory effects against influenza virus in …
Apolipoproteins and cancer
…, J Yi, W Li, X Zheng, J Liu, J Wang, G Du - Cancer …, 2019 - Wiley Online Library
The role of apolipoproteins in cardiovascular disease has been well investigated, but their
participation in cancer has only been explored in a few published studies which showed a …
participation in cancer has only been explored in a few published studies which showed a …