Breast cancer has been shown to live in the tumor microenvironment, which consists of not
only breast cancer cells themselves but also a significant amount of pathophysiologically …

As a cell proliferation biomarker, Ki-67 is principally used in ER+/HER2− breast cancer.
However, the importance and the best cutoff point of Ki-67 in triple-negative breast cancer (TNBC…

CD44+/CD24−/low tumor cells or aldehyde dehydrogenase 1 (ALDH1) positive tumor cells
are considered cancer stem cells (CSCs) that possess the properties of self-renewal and …

Metastasis and chemoresistance are two major causes of breast cancer death. We show
here that the chemokine receptor CXCR2 was overexpressed in breast cancer cell lines and …

No standard first‐line treatment exists for patients with metastatic triple‐negative breast
cancer (mTNBC). In this single‐arm, phase II study (NCT00601159), we evaluated the efficacy …

The genetic etiology of hereditary breast cancer has not been fully elucidated. Although
germline mutations of high-penetrance genes such as BRCA1/2 are implicated in development …

Introduction Investigate the patterns of mammographically detected calcifications before and
after neoadjuvant chemotherapy (NACT) to determine their value for efficacy evaluation and …

We retrospective analyzed triple negative breast cancer (TNBC) patients who received
either taxane-based or anthracycline-based neoadjuvant chemotherapy, evaluated whether …

Background The aim of this study was to investigate the predictive value of early changes in
18 F‐fluoroestradiol (FES) positron emission tomography (PET)/computed tomography (CT) …

Background Little is known regarding the clinicopathologic characteristics, oncologic outcomes,
and treatment strategies that could be ascribed to BRCA mutation in early-onset triple-…