There are remarkable disparities among patients of different races with prostate cancer;
however, the mechanism underlying this difference remains unclear. Here, we present a …

Prostate cancer shows remarkable clinical heterogeneity, which manifests in spatial and
clonal genomic diversity. By contrast, the transcriptomic heterogeneity of prostate tumours is …

Purpose : To understand the role of MALAT-1 in prostate cancer we evaluated its expression
in prostate cancer tissues and cell lines. We also studied the therapeutic effects of MALAT-1 …

Examining plasma RNA is an emerging non-invasive diagnosis technique. However,
whether tumour-derived long non-coding RNAs (lncRNAs) in plasma can be used as a novel …

Objective Emerging evidences implicate long noncoding RNAs (lncRNAs) are deregulated
in cancer development. The purpose of the current study is to investigate the role of new …

The current strategy for diagnosing prostate cancer (PCa) is mainly based on the serum
prostate-specific antigen (PSA) test. However, PSA has low specificity and has led to numerous …

Prostate cancer is a highly prevalent tumor affecting millions of men worldwide, but poor
understanding of its pathogenesis has limited effective clinical management of patients. In …

In-depth delineation of lipid metabolism in prostate cancer (PCa) is significant to open new
insights into prostate tumorigenesis and progression, and provide potential biomarkers with …

Metastasis is a predominant cause of death for prostate cancer (PCa) patients; however, the
underlying mechanisms are poorly understood. We report that monoamine oxidase A (…

Genetic alterations drive metabolic reprograming to meet increased biosynthetic precursor
and energy demands for cancer cell proliferation and survival in unfavorable environments. A …