Comparative analysis of theophylline and cholera toxin in rat colon reveals an induction of sealing tight junction proteins

AG Markov, EL Falchuk, NM Kruglova… - … -European Journal of …, 2014 - Springer
Claudin tight junction proteins have been identified to primarily determine intestinal epithelial
barrier properties. While functional contribution of single claudins has been characterized …

[HTML][HTML] Molecular characterization of barrier properties in follicle-associated epithelium of porcine peyer's patches reveals major sealing function of claudin-4

J Radloff, EL Falchuk, AG Markov… - Frontiers in Physiology, 2017 - frontiersin.org
The pig represents a preferred model for the analysis of intestinal immunology. However,
the barrier of the follicle-associated epithelium (FAE) covering porcine Peyer's patches (PP) …

[HTML][HTML] Increased paracellular permeability of tumor-adjacent areas in 1, 2-dimethylhydrazine-induced colon carcinogenesis in rats

VV Bekusova, EL Falchuk, LS Okorokova… - Cancer Biology & …, 2018 - ncbi.nlm.nih.gov
Objective: The morphology and functions of the proximal and distal large intestine are not the
same. The incidence of colorectal cancer in these regions is also different, as tumors more …

The study of barrier characteristics of peyer's patches epithelium in rats

E Falchuk, A Markov - Biological Communications, 2015 - biocomm.spbu.ru
The aim of the study was to investigate the barrier function of Peyer’s patches epithelium,
which covers the clusters of organized lymphoid tissues in the small intestinal. We used the …

Modulation of the tight junctions of the Caco-2 cell monolayers by H2-antagonists

LSL Gan, S Yanni, DR Thakker - Pharmaceutical research, 1998 - Springer
Purpose. The tight junctions in the intestinal epithelium represent highly specialized
intercellular junctions. Ranitidine, an H 2 -antagonist, causes a tightening of the tight junctions. …

Caprate modulates intestinal barrier function in porcine peyer's patch follicle-associated epithelium

J Radloff, V Cornelius, AG Markov… - International Journal of …, 2019 - mdpi.com
Background: Many food components influence intestinal epithelial barrier properties and might
therefore also affect susceptibility to the development of food allergies. Such allergies are …

Changes in cytoplasmic volume are sufficient to drive spindle scaling

J Hazel, K Krutkramelis, P Mooney, M Tomschik… - Science, 2013 - science.org
The mitotic spindle must function in cell types that vary greatly in size, and its dimensions
scale with the rapid, reductive cell divisions that accompany early stages of development. The …

Molecular and functional analysis of the porcine and murine small intestinal tight junction

J Radloff - 2018 - refubium.fu-berlin.de
The tight junction (TJ) surrounds epithelial cells in the upper third of the lateral cellular
membrane. It is formed by different proteins that are anchored within the membrane of epithelial …

3D TOCSY-HSQC NMR for metabolic flux analysis using non-uniform sampling

PN Reardon, CL Marean-Reardon… - Analytical …, 2016 - ACS Publications
Evgeny Tishchenko for assistance with pulse sequence programing. Funding for this
work was provided in part by the William Wiley Postdoctoral Fellowship from EMSL to PNR …

Dietary zinc modifies diabetic-induced renal pathology in rats

WM Elsaed, HA Mohamed - Renal failure, 2017 - Taylor & Francis
This study was conducted to investigate how far dietary zinc (Zn) modifies the histomorphological
alterations induced by diabetes in rat kidneys. The animals were divided into negative …