Roles of RNA methylation by means of N6-methyladenosine (m6A) in human cancers

S Wang, C Sun, J Li, E Zhang, Z Ma, W Xu, H Li, M Qiu… - Cancer letters, 2017 - Elsevier
Reversible methylation by means of N6-methyladenosine (m 6 A) is the most prevalent
internal modification in mammalian mRNA. This RNA chemical mark is created by proteins that …

H3K27 acetylation activated-long non-coding RNA CCAT1 affects cell proliferation and migration by regulating SPRY4 and HOXB13 expression in esophageal …

E Zhang, L Han, D Yin, X He, L Hong, X Si… - Nucleic acids …, 2017 - academic.oup.com
Recently, long non-coding RNAs (lncRNAs) have been shown to have important regulatory
roles in human cancer biology. In our study, we found that lncRNA CCAT1, whose …

[HTML][HTML] A novel long noncoding RNA HOXC-AS3 mediates tumorigenesis of gastric cancer by binding to YBX1

E Zhang, X He, C Zhang, J Su, X Lu, X Si, J Chen… - Genome biology, 2018 - Springer
Background Recently, increasing evidence shows that long noncoding RNAs (lncRNAs)
play a significant role in human tumorigenesis. However, the function of lncRNAs in human …

The circular RNA circPRKCI promotes tumor growth in lung adenocarcinoma

…, W Xia, R Chen, S Wang, Y Xu, Z Ma, W Xu, E Zhang… - Cancer research, 2018 - AACR
Somatic copy number variations (CNV) may drive cancer progression through both coding
and noncoding transcripts. However, noncoding transcripts resulting from CNV are largely …

[HTML][HTML] Cancer-associated fibroblast-specific lncRNA LINC01614 enhances glutamine uptake in lung adenocarcinoma

…, H Chen, S Wang, F Meng, C Wang, E Zhang… - Journal of hematology & …, 2022 - Springer
Background Besides featured glucose consumption, recent studies reveal that cancer cells
might prefer “addicting” specific energy substrates from the tumor microenvironment (TME); …

Long noncoding RNA GAS5 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer

D Yin, X He, E Zhang, R Kong, W De, Z Zhang - Medical oncology, 2014 - Springer
Colorectal cancer (CRC) is the third most common type of cancer worldwide. Recent studies
have shown that lncRNAs play important roles in carcinogenesis. The aim of this study was …

[HTML][HTML] LncRNA LINC00969 promotes acquired gefitinib resistance by epigenetically suppressing of NLRP3 at transcriptional and posttranscriptional levels to inhibit …

J Dai, T Qu, D Yin, Y Cui, C Zhang, E Zhang… - Cell death & …, 2023 - nature.com
Epidermal growth factor receptor-tyrosine kinase inhibitor (EGFR-TKI) treatment prolongs
the survival of lung cancer patients harbouring activating EGFR mutations. However, …

Decreased expression of long noncoding RNA MEG3 affects cell proliferation and predicts a poor prognosis in patients with colorectal cancer

D Yin, Z Liu, E Zhang, R Kong, Z Zhang, R Guo - Tumor Biology, 2015 - Springer
Colorectal cancer (CRC) remains an important public health problem in the world. Long
noncoding RNA (lncRNA) is an RNA molecular that is longer than 200 nucleotides and cannot …

[HTML][HTML] LncRNA H19 confers chemoresistance in ERα-positive breast cancer through epigenetic silencing of the pro-apoptotic gene BIK

X Si, R Zang, E Zhang, Y Liu, X Shi, E Zhang, L Shao… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Breast cancer is a common malignancy in women. Acquisition of drug resistance is one of
the main obstacles encountered in breast cancer therapy. Long non-coding RNA (lncRNA) …

[HTML][HTML] Long noncoding RNA AFAP1-AS1 predicts a poor prognosis and regulates non–small cell lung cancer cell proliferation by epigenetically repressing p21 …

…, X Lu, J Su, X He, W De, J Yang, W Li, L Han, E Zhang - Molecular cancer, 2018 - Springer
Background Mounting evidence indicates that long noncoding RNAs (lncRNAs) could play
a pivotal role in cancer biology. However, the role and molecular mechanism and global …