Muscle and neuronal nicotinic acetylcholine receptors: structure, function and pathogenicity
D Kalamida, K Poulas, V Avramopoulou… - The FEBS …, 2007 - Wiley Online Library
Nicotinic acetylcholine receptors (nAChRs) are integral membrane proteins and prototypic
members of the ligand‐gated ion‐channel superfamily, which has precursors in the …
members of the ligand‐gated ion‐channel superfamily, which has precursors in the …
[HTML][HTML] Autophagosome proteins LC3A, LC3B and LC3C have distinct subcellular distribution kinetics and expression in cancer cell lines
MI Koukourakis, D Kalamida, A Giatromanolaki… - PloS one, 2015 - journals.plos.org
LC3s (MAP1-LC3A, B and C) are structural proteins of autophagosomal membranes, widely
used as biomarkers of autophagy. Whether these three LC3 proteins have a similar …
used as biomarkers of autophagy. Whether these three LC3 proteins have a similar …
Increased expression of transcription factor EB (TFEB) is associated with autophagy, migratory phenotype and poor prognosis in non-small cell lung cancer
A Giatromanolaki, D Kalamida, E Sivridis… - Lung cancer, 2015 - Elsevier
Objectives We investigated the role of lysosomal biogenesis and hydrolase activity in the
clinical behavior and postoperative outcome of lung cancer. Materials and methods Using …
clinical behavior and postoperative outcome of lung cancer. Materials and methods Using …
Autophagy and lysosomal related protein expression patterns in human glioblastoma
…, E Sivridis, A Mitrakas, D Kalamida… - Cancer biology & …, 2014 - Taylor & Francis
Glioblastoma cells are resistant to apoptotic stimuli with autophagic death prevailing under
cytotoxic stress. Autophagy interfering agents may represent a new strategy to test in …
cytotoxic stress. Autophagy interfering agents may represent a new strategy to test in …
[HTML][HTML] Fever-range hyperthermia vs. hypothermia effect on cancer cell viability, proliferation and HSP90 expression
D Kalamida, IV Karagounis, A Mitrakas, S Kalamida… - PLoS …, 2015 - journals.plos.org
Purpose The current study examines the effect of fever-range hyperthermia and mild hypothermia
on human cancer cells focusing on cell viability, proliferation and HSP90 expression. …
on human cancer cells focusing on cell viability, proliferation and HSP90 expression. …
Hypoxia-inducible proteins HIF1α and lactate dehydrogenase LDH5, key markers of anaerobic metabolism, relate with stem cell markers and poor post-radiotherapy …
MI Koukourakis, C Kakouratos, D Kalamida… - … journal of radiation …, 2016 - Taylor & Francis
Purpose: To assess whether anaerobic metabolism, proliferation activity and stem cell content
are linked with radioresistance in bladder cancer. Materials and methods: Tissue sections …
are linked with radioresistance in bladder cancer. Materials and methods: Tissue sections …
[HTML][HTML] Metabolic cooperation between co-cultured lung cancer cells and lung fibroblasts
MI Koukourakis, D Kalamida, AG Mitrakas… - Laboratory …, 2017 - Elsevier
Cooperation of cancer cells with stromal cells, such as cancer-associated fibroblasts (CAFs),
has been revealed as a mechanism sustaining cancer cell survival and growth. In the …
has been revealed as a mechanism sustaining cancer cell survival and growth. In the …
Transcription factor EB expression in early breast cancer relates to lysosomal/autophagosomal markers and prognosis
A Giatromanolaki, E Sivridis, D Kalamida… - Clinical breast …, 2017 - Elsevier
Background Disrupting the autophagic balance to trigger autophagic death may open new
strategies for cancer therapy. Transcription factor EB (TFEB) is a master regulator of …
strategies for cancer therapy. Transcription factor EB (TFEB) is a master regulator of …
[HTML][HTML] CYP17A1 and androgen-receptor expression in prostate carcinoma tissues and cancer cell lines
A Giatromanolaki, V Fasoulaki, D Kalamida… - Current …, 2019 - karger.com
Background: CYP17A1 is involved in the steroidogenesis of dehydroepiandrosterone and
androstenedione. CYP17A is a target for the hormonal treatment of prostate cancer (PCa). …
androstenedione. CYP17A is a target for the hormonal treatment of prostate cancer (PCa). …
[HTML][HTML] Repression of the autophagic response sensitises lung cancer cells to radiation and chemotherapy
IV Karagounis, D Kalamida, A Mitrakas… - British journal of …, 2016 - nature.com
Background: The cellular autophagic response to radiation is complex. Various cells and
tissues respond differentially to radiation, depending on both the dose of exposure and the time …
tissues respond differentially to radiation, depending on both the dose of exposure and the time …
