User profiles for Daolin Tang

Daolin Tang

UT Southwestern Medical Center
Verified email at utsouthwestern.edu
Cited by 79821

[PDF][PDF] Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease

…, J Park, Q Ran, CS Rosenfeld, K Salnikow, D Tang… - Cell, 2017 - cell.com
Ferroptosis is a form of regulated cell death characterized by the iron-dependent accumulation
of lipid hydroperoxides to lethal levels. Emerging evidence suggests that ferroptosis …

Endogenous HMGB1 regulates autophagy

D Tang, R Kang, KM Livesey, CW Cheh… - Journal of Cell …, 2010 - rupress.org
Autophagy clears long-lived proteins and dysfunctional organelles and generates substrates
for adenosine triphosphate production during periods of starvation and other types of …

The hallmarks of COVID-19 disease

D Tang, P Comish, R Kang - PLoS pathogens, 2020 - journals.plos.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a novel coronavirus that
has caused a worldwide pandemic of the human respiratory illness COVID-19, resulting in a …

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

…, A Strasser, G Szabadkai, SWG Tait, D Tang… - Cell Death & …, 2018 - nature.com
Over the past decade, the Nomenclature Committee on Cell Death (NCCD) has formulated
guidelines for the definition and interpretation of cell death from morphological, biochemical, …

Ferroptosis: molecular mechanisms and health implications

D Tang, X Chen, R Kang, G Kroemer - Cell research, 2021 - nature.com
Cell death can be executed through different subroutines. Since the description of ferroptosis
as an iron-dependent form of non-apoptotic cell death in 2012, there has been mounting …

PAMP s and DAMP s: Signal 0s that spur autophagy and immunity

D Tang, R Kang, CB Coyne, HJ Zeh… - Immunological …, 2012 - Wiley Online Library
Pathogen‐associated molecular pattern molecules ( PAMP s) are derived from microorganisms
and recognized by pattern recognition receptor ( PRR )‐bearing cells of the innate …

HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

D Tang, R Kang, CW Cheh, KM Livesey, X Liang… - Oncogene, 2010 - nature.com
The functional relationship and cross-regulation between autophagy and apoptosis is
complex. In this study we show that the high-mobility group box 1 protein (HMGB1) is a redox-…

[PDF][PDF] Activation of the p62‐Keap1‐NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

…, Z Ou, R Chen, X Niu, D Chen, R Kang, D Tang - …, 2016 - Wiley Online Library
Ferroptosis is a recently recognized form of regulated cell death caused by an iron‐dependent
accumulation of lipid reactive oxygen species. However, the molecular mechanisms …

Broadening horizons: the role of ferroptosis in cancer

X Chen, R Kang, G Kroemer, D Tang - Nature reviews Clinical oncology, 2021 - nature.com
The discovery of regulated cell death processes has enabled advances in cancer treatment.
In the past decade, ferroptosis, an iron-dependent form of regulated cell death driven by …

Ferroptosis: machinery and regulation

X Chen, J Li, R Kang, DJ Klionsky, D Tang - Autophagy, 2021 - Taylor & Francis
Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death caused by lipid
peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron-…