Highly Efficient and Selective Dissolution Separation of Fission Products by an Ionic Liquid [Hbet][Tf2N]: A New Approach to Spent Nuclear Fuel Recycling
FL Fan, Z Qin, SW Cao, CM Tan, QG Huang… - Inorganic …, 2018 - ACS Publications
Here, we propose the use of carboxyl-functionalized ionic liquid, [Hbet][Tf 2 N], to separate
the fission products from spent nuclear fuels. This innovative method allows the selective …
the fission products from spent nuclear fuels. This innovative method allows the selective …
Design and synthesis of 2-(4, 5, 6, 7-tetrahydrothienopyridin-2-yl)-benzoimidazole carboxamides as novel orally efficacious Poly (ADP-ribose) polymerase (PARP) …
X Chen, X Huan, Q Liu, Y Wang, Q He, C Tan… - European journal of …, 2018 - Elsevier
The nuclear protein poly(ADP-ribose) polymerases-1/2 (PARP-1/2) are involved in DNA
repair damaged by endogenous or exogenous process. And PARP-1/2 inhibitors have been …
repair damaged by endogenous or exogenous process. And PARP-1/2 inhibitors have been …
Identification of methyl (5-(6-((4-(methylsulfonyl) piperazin-1-yl) methyl)-4-morpholinopyrrolo [2, 1-f][1, 2, 4] triazin-2-yl)-4-(trifluoromethyl) pyridin-2-yl) carbamate …
HY Xiang, X Wang, YH Chen, X Zhang, C Tan… - European Journal of …, 2021 - Elsevier
In various human cancers, PI3Ks pathway is ubiquitously dysregulated and thus become a
promising anti-cancer target. To discover new potent and selective PI3K inhibitors as …
promising anti-cancer target. To discover new potent and selective PI3K inhibitors as …
[HTML][HTML] Novel PARP1/2 inhibitor mefuparib hydrochloride elicits potent in vitro and in vivo anticancer activity, characteristic of high tissue distribution
…, CH Chen, SS Song, YQ Wang, XM Liao, C Tan… - Oncotarget, 2017 - ncbi.nlm.nih.gov
The approval of poly (ADP-ribose) polymerase (PARP) inhibitor AZD2281 in 2014 marked
the successful establishment of the therapeutic strategy targeting homologous recombination …
the successful establishment of the therapeutic strategy targeting homologous recombination …
[HTML][HTML] Simultaneous inhibition of PI3Kα and CDK4/6 synergistically suppresses KRAS-mutated non-small cell lung cancer
…, X Li, X Liu, Y Chen, C Yang, C Tan… - Cancer biology & …, 2019 - ncbi.nlm.nih.gov
Objective Activating KRAS mutations are the most common drivers in the development of
non-small cell lung cancer (NSCLC). However, unsuccess of treatment by direct inhibition of …
non-small cell lung cancer (NSCLC). However, unsuccess of treatment by direct inhibition of …
OsPOP5, A Prolyl Oligopeptidase Family Gene from Rice Confers Abiotic Stress Tolerance in Escherichia coli
CM Tan, RJ Chen, JH Zhang, XL Gao, LH Li… - International journal of …, 2013 - mdpi.com
The prolyl oligopeptidase family, which is a group of serine peptidases, can hydrolyze
peptides smaller than 30 residues. The prolyl oligopeptidase family in plants includes four …
peptides smaller than 30 residues. The prolyl oligopeptidase family in plants includes four …
Natural product-based design, synthesis and biological evaluation of anthra [2, 1-d] thiazole-6, 11-dione derivatives from rhein as novel antitumour agents
…, ZZ Yue, JX Li, C Tan, ZH Miao, WF Tan… - European Journal of …, 2014 - Elsevier
Two series of novel 2-substituted 5, 7-dihydroxyanthra [2, 1-d] thiazole-6, 11-dione
derivatives from natural rhein were designed, synthesized and evaluated for their antitumour …
derivatives from natural rhein were designed, synthesized and evaluated for their antitumour …
Gas-phase chemistry of technetium carbonyl complexes
…, H Haba, Y Komori, SW Cao, XL Wu, CM Tan - Physical Chemistry …, 2015 - pubs.rsc.org
Gas-phase chemical behaviors of short-lived technetium carbonyl complexes were studied
using a low temperature isothermal chromatograph (IC) coupled with a 252Cf spontaneous …
using a low temperature isothermal chromatograph (IC) coupled with a 252Cf spontaneous …
Adaptive resistance to PI3Kα-selective inhibitor CYH33 is mediated by genomic and transcriptomic alterations in ESCC cells
…, L Hu, X Zhang, Y Wang, L Xu, C Yang, C Tan… - Cell Death & …, 2021 - nature.com
Phosphoinositide-3 kinase alpha-specific inhibitors (PI3Kαi) displayed promising potential
for the treatment of esophageal squamous cell carcinoma (ESCC) with frequent activation in …
for the treatment of esophageal squamous cell carcinoma (ESCC) with frequent activation in …
Decrease in phosphorylated ERK indicates the therapeutic efficacy of a clinical PI3Kα-selective inhibitor CYH33 in breast cancer
…, Y Wang, Y Chen, B Wang, Y Wang, Y Chen, C Tan… - Cancer Letters, 2018 - Elsevier
PI3Ks are frequently hyper-activated in breast cancer and targeting PI3Kα has exhibited
promising but variable response in preclinical and clinical settings. CYH33 is a novel PI3Kα-…
promising but variable response in preclinical and clinical settings. CYH33 is a novel PI3Kα-…
