Human gut microbiota and gastrointestinal cancer
Human gut microbiota play an essential role in both healthy and diseased states of humans.
In the past decade, the interactions between microorganisms and tumors have attracted …
In the past decade, the interactions between microorganisms and tumors have attracted …
[HTML][HTML] Single-cell RNA sequencing reveals a pro-invasive cancer-associated fibroblast subgroup associated with poor clinical outcomes in patients with gastric …
…, Y Xiao, J Guo, B Wu, X Li, W Zhou, J Li, Z Li, C Bai… - Theranostics, 2022 - ncbi.nlm.nih.gov
Background: The protumor activities of cancer-associated fibroblasts (CAFs) suggest that
they are potential therapeutic targets for the treatment of cancer. The mechanism of CAF …
they are potential therapeutic targets for the treatment of cancer. The mechanism of CAF …
Efficacy and safety of a novel anti‐HER2 therapeutic antibody RC48 in patients with HER2‐overexpressing, locally advanced or metastatic gastric or …
…, R Xu, L Zhang, E Li, Y Sun, G Yu, C Bai… - Cancer …, 2021 - Wiley Online Library
Background Current treatment options for human epidermal growth factor receptor 2 (HER2)‐overexpressing
gastric cancer at third‐line have shown limited clinical benefit. Further, …
gastric cancer at third‐line have shown limited clinical benefit. Further, …
Surufatinib in advanced extrapancreatic neuroendocrine tumours (SANET-ep): a randomised, double-blind, placebo-controlled, phase 3 study
…, J Li, C Bai, Y Chi, Z Li, N Xu, E Li, T Liu, Y Bai… - The Lancet …, 2020 - thelancet.com
Background Therapeutic options for advanced neuroendocrine tumours (NETs) are limited.
We investigated the efficacy and safety of surufatinib (HMPL-012, sulfatinib) in patients with …
We investigated the efficacy and safety of surufatinib (HMPL-012, sulfatinib) in patients with …
Surufatinib in advanced pancreatic neuroendocrine tumours (SANET-p): a randomised, double-blind, placebo-controlled, phase 3 study
J Xu, L Shen, C Bai, W Wang, J Li, X Yu, Z Li… - The Lancet …, 2020 - thelancet.com
Background Surufatinib showed superior efficacy in extrapancreatic neuroendocrine tumours
(NETs) in the phase 3 SANET-ep study. In SANET-p, we aimed to assess the efficacy and …
(NETs) in the phase 3 SANET-ep study. In SANET-p, we aimed to assess the efficacy and …
Clinical and biomarker analyses of sintilimab versus chemotherapy as second-line therapy for advanced or metastatic esophageal squamous cell carcinoma: a …
…, N Xu, J Xiao, Q Gao, Y Liu, T Zhang, Y Bai… - Nature …, 2022 - nature.com
This randomized, open-label, multi-center phase 2 study (NCT03116152) assessed
sintilimab, a PD-1 inhibitor, versus chemotherapy in patients with esophageal squamous cell …
sintilimab, a PD-1 inhibitor, versus chemotherapy in patients with esophageal squamous cell …
[HTML][HTML] Clinical activity and safety of penpulimab (Anti-PD-1) with anlotinib as first-line therapy for unresectable hepatocellular carcinoma: an open-label, multicenter …
…, Y Bai, S Yang, C Bai, A Zang, S Jiao, L Bai - Frontiers in …, 2021 - frontiersin.org
Objective This study aims to assess the efficacy and safety of penpulimab (a humanized anti-PD-1
IgG1 antibody) with anlotinib in the first-line treatment of Chinese patients with uHCC. …
IgG1 antibody) with anlotinib in the first-line treatment of Chinese patients with uHCC. …
Cucurbitaceae genome evolution, gene function, and molecular breeding
…, Y Zheng, J Guo, S Yuan, A Fu, C Bai… - Horticulture …, 2022 - academic.oup.com
Cucurbitaceae is one of the most genetically diverse plant families in the world. Many of
them are important vegetables or medicinal plants and are widely distributed worldwide. The …
them are important vegetables or medicinal plants and are widely distributed worldwide. The …
MicroRNA-1246 enhances migration and invasion through CADM1 in hepatocellular carcinoma
Z Sun, C Meng, S Wang, N Zhou, M Guan, C Bai, S Lu… - BMC cancer, 2014 - Springer
Background The aberrant expression of microRNAs has been demonstrated to play a crucial
role in the initiation and progression of hepatocarcinoma. miR-1246 expression in High …
role in the initiation and progression of hepatocarcinoma. miR-1246 expression in High …
Expert consensus on multidisciplinary therapy of colorectal cancer with lung metastases (2019 edition)
…, D Wan, J He, J Wang, Y Ba, C Bai, L Bai, W Bai… - Journal of hematology & …, 2019 - Springer
The lungs are the second most common site of metastasis for colorectal cancer (CRC) after
the liver. Rectal cancer is associated with a higher incidence of lung metastases compared to …
the liver. Rectal cancer is associated with a higher incidence of lung metastases compared to …
