[HTML][HTML] Fanconi anemia pathway: mechanisms of breast cancer predisposition development and potential therapeutic targets

CB Fang, HT Wu, ML Zhang, J Liu… - Frontiers in cell and …, 2020 - frontiersin.org
The maintenance of genomic stability is crucial for species survival, and its failure is closely
associated with tumorigenesis. The Fanconi anemia (FA) pathway, involving 22 identified …

H. pylori‐induced NF‐κB‐PIEZO1‐YAP1‐CTGF axis drives gastric cancer progression and cancer‐associated fibroblast‐mediated tumour microenvironment …

…, F Xie, JSH Kwan, WN Chan, C Fang… - Clinical and …, 2023 - Wiley Online Library
Background Gastric cancer (GC) is one of the most common tumours in East Asia countries
and is associated with Helicobacter pylori infection. H. pylori utilizes virulence factors, CagA …

The molecular classification of cancer‐associated fibroblasts on a pan‐cancer single‐cell transcriptional atlas

…, RWM Lung, C Chow, Z Zhang, C Fang… - Clinical and …, 2023 - Wiley Online Library
Background Cancer‐associated fibroblasts (CAFs), integral to the tumour microenvironment,
are pivotal in cancer progression, exhibiting either pro‐tumourigenic or anti‐tumourigenic …

[HTML][HTML] Insight into the evolution of breast cancer driven by genetic alterations

C Fang, X Fan, W Lin, G Zhang - Cancer Biology & Medicine, 2023 - ncbi.nlm.nih.gov
Breast cancer originates primarily from the epithelial cells of the mammary gland. Repeated
mammary gland expansion and degeneration are accompanied by an increased risk of …

Breast cancer metastases to the thyroid and stomach: A case report

X Bai, C Fang, B Liu, J Huagn, X Chen… - Oncology …, 2023 - spandidos-publications.com
The most common sites of metastasis for breast cancer are the soft tissues, bones, lungs, liver
and brain; however, metastases to the gastrointestinal tract and thyroid gland from breast …

Numerical Study on the Light Extraction Efficiency and Angular Energy Distribution of Micro-LEDs

Z Fan, W Chen, F Qiu, C Fang, B Xiang… - 2021 IEEE 6th …, 2021 - ieeexplore.ieee.org
Micro light emitting diodes (Micro-LEDs) possess advantages of high optical efficiency, high
resolution and long lifetime, leading to a very broad application prospect in the future. This …

Abstract PO1-13-12: Mechanistic Analysis and Potential Therapeutic Implications in Breast Cancer with Fibrotic Focus

C Fang, JYS Tsang, GMK Tse - Cancer Research, 2024 - AACR
A fibrotic focus (FF) is a scar-like region that forms in the center of carcinoma due to
excessive tumor stroma formation. In our earlier studies, we found FF as an independent poor …

The role and mechanism of m6A methylation modification of LncRNA-ATB in regulating the invasion and metastasis of colorectal cancer

Y Lang#, JL Lin#, JP Kang, L Yang, D Zhou, CB Fang*… - Cancer Research, 2024 - AACR
Background: The epigenetic modification of LncRNA N6-methyladenosine (m6A) methylation
plays a wide role in the invasion and metastasis of various malignant tumors. However, the …

Quantification of histone methylation regulator-associated modification patterns was a potential biomarker for prognosis and associated with immunotherapy in gastric …

J Kang, L Yang, J Lin, D Zhou, C Fang, F Ye, W Tang - Cancer Research, 2022 - AACR
Background: Histone methylation (HM) is an abundant form of histone modification and recent
studies have highlighted it strongly related to tumorigenicity and progression. However, …

Abstract LB-302: Whole genome sequencing reveals a significant role of ZNFs-PHLPP2-AKT axis in familial breast cancer of chaoshan area

CB Fang, QQ Ye, J Liu, GJ Zhang - Cancer Research, 2019 - AACR
Introduction Up to 15% cases of breast cancer are familial. However, the two most prevalent
susceptibility genes, BRCA1 and BRCA2, only account for 25% of the familial cases. To this …