[HTML][HTML] The role of CXCR3 and its ligands in cancer

…, Y Zhang, S Wang, H Ni, P Zhao, G Chen, B Xu… - Frontiers in …, 2022 - frontiersin.org
Chemokines are a class of small cytokines or signaling proteins that are secreted by cells.
Owing to their ability to induce directional chemotaxis of nearby responding cells, they are …

[HTML][HTML] Circulating and tumor-infiltrating Tim-3 in patients with colorectal cancer

B Xu, L Yuan, Q Gao, P Yuan, P Zhao, H Yuan, H Fan… - Oncotarget, 2015 - ncbi.nlm.nih.gov
T-cell exhaustion represents a progressive loss of T-cell function. The inhibitory receptor PD-1
is known to negatively regulate CD8+ T cell responses directed against tumor antigen, but …

[HTML][HTML] LncRNA LINC00173 enhances triple-negative breast cancer progression by suppressing miR-490-3p expression

H Fan, J Yuan, X Li, Y Ma, X Wang, B Xu, X Li - Biomedicine & …, 2020 - Elsevier
Long non-coding RNA (lncRNA) LINC00173 has been previously shown to promote
chemoresistance and progression of small-cell lung cancer. Herein, we examine the clinical …

[HTML][HTML] miR-542-3p inhibits colorectal cancer cell proliferation, migration and invasion by targeting OTUB1

…, Z Wang, Z Run, G Chen, P Zhao, B Xu - American journal of …, 2017 - ncbi.nlm.nih.gov
Although miR-542-3p has been found to be aberrantly downregulated in variety of human
tumors, little is known about its role in colorectal cancer (CRC). This study was designed to …

Prognostic value of platelet-to-lymphocyte ratio, neutrophil-to-lymphocyte ratio, and lymphocyte-to-white blood cell ratio in colorectal cancer patients who received …

W Jia, L Yuan, H Ni, B Xu… - Technology in cancer …, 2021 - journals.sagepub.com
Background: The objective of this study was to assess the prognostic value of pretreatment
platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and lymphocyte-to-…

T Cells Expanded from PD-1+ Peripheral Blood Lymphocytes Share More Clones with Paired Tumor-Infiltrating Lymphocytes

…, Y Wang, Y Zhang, J Guo, G Chen, P Qin, B Xu… - Cancer Research, 2021 - AACR
This study harnesses the tumor reactivity of PD-1 + PBLs, developing a method to expand T
cells from these clones as a potential therapeutic strategy and TIL substitute in patients with …

[HTML][HTML] Silencing of ribosomal protein L34 (RPL34) inhibits the proliferation and invasion of esophageal cancer cells

…, J Li, Y Jia, J Wu, L Yuan, M Li, J Wei, B Xu - Oncology …, 2017 - ncbi.nlm.nih.gov
Ribosomal protein L34 (RPL34) belongs to the L34E family of ribosomal proteins and contains
a zinc finger motif. Aberrant expression of RPL34 has been reported in several human …

[HTML][HTML] The role of intestinal flora on tumorigenesis, progression, and the efficacy of PD-1/PD-L1 antibodies in colorectal cancer

S Wang, B Xu, Y Zhang, G Chen, P Zhao… - Cancer Biology & …, 2024 - ncbi.nlm.nih.gov
Intestinal flora affects the maturation of the host immune system, serves as a biomarker and
efficacy predictor in the immunotherapy of several cancers, and has an important role in the …

[HTML][HTML] Tumor-infiltrating CD4+ T cells in patients with gastric cancer

L Yuan, B Xu, P Yuan, J Zhou, P Qin, L Han… - Cancer cell …, 2017 - Springer
Background T lymphocytes play an indispensably important role in clearing virus and tumor
antigen. There is little knowledge about impacts of inhibitory molecules with cytokine on …

[HTML][HTML] Sulforaphene induces apoptosis and inhibits the invasion of esophageal cancer cells through MSK2/CREB/Bcl-2 and cadherin pathway in vivo and in vitro

C Zhang, J Zhang, Q Wu, B Xu, G Jin, Y Qiao… - Cancer Cell …, 2019 - Springer
Background As a novel type of isothiocyanate derived from radish seeds from cruciferous
vegetables, sulforaphene (SFE, 4-methylsufinyl-3-butenyl isothiocyanate) has various …