Circulating miRNAs are correlated with tumor progression in prostate cancer

…, T Schlomm, M Fälth, A Haese… - … journal of cancer, 2011 - Wiley Online Library
Circulating miRNAs have recently been indicated as practicable and promising biomarkers
for noninvasive diagnosis in various tumor entities. However, cell‐free miRNAs have not …

Clinical utility of the PCA3 urine assay in European men scheduled for repeat biopsy

A Haese, A de la Taille, H Van Poppel, M Marberger… - European urology, 2008 - Elsevier
BACKGROUND: The Prostate CAncer gene 3 (PCA3) assay has shown promise as an aid
in prostate cancer (pCA) diagnosis in identifying men with a high probability of a positive (…

High level PSMA expression is associated with early PSA recurrence in surgically treated prostate cancer

…, M Graefen, G Salomon, T Steuber, A Haese… - The …, 2011 - Wiley Online Library
BACKGROUND Prostate specific membrane antigen (PSMA) is a suggested target for
antibody‐based therapy of prostate cancer potentially involved in the regulation of cell migration. …

Clinical utility of quantitative Gleason grading in prostate biopsies and prostatectomy specimens

…, S Minner, MC Tsourlakis, V Chirico, A Haese… - European urology, 2016 - Elsevier
Background Gleason grading is the strongest prognostic parameter in prostate cancer.
Gleason grading is categorized as Gleason ≤6, 3 + 4, 4 + 3, 8, and 9–10, but there is variability …

High incidence of prostate cancer detected by saturation biopsy after previous negative biopsy series

…, M Graefen, FKH Chun, A Erbersdobler, A Haese… - European urology, 2006 - Elsevier
OBJECTIVES: We explored the yield of saturation biopsy and developed a nomogram predicting
the probability of prostate cancer (PCa) on the basis of saturation biopsy. MATERIALS …

Serum isoform [− 2] proPSA derivatives significantly improve prediction of prostate cancer at initial biopsy in a total PSA range of 2–10 ng/ml: a multicentric European …

M Lazzeri, A Haese, A de la Taille, JP Redorta… - European urology, 2013 - Elsevier
BACKGROUND: Strategies to reduce prostate-specific antigen (PSA)–driven prostate cancer
(PCa) overdiagnosis and overtreatment seem to be necessary. OBJECTIVE: To test the …

Neurovascular structure-adjacent frozen-section examination (NeuroSAFE) increases nerve-sparing frequency and reduces positive surgical margins in open and …

…, L Budäus, S Steurer, C Wittmer, S Minner, A Haese… - European urology, 2012 - Elsevier
BACKGROUND: Intraoperative frozen-section analysis allows real-time histologic
assessment of surgical margins (SMs) and identification of candidates for nerve-sparing (NS) …

Full functional-length urethral sphincter preservation during radical prostatectomy

…, T Steuber, G Salomon, O Engel, U Michl, A Haese… - European urology, 2011 - Elsevier
BACKGROUND: A key prerequisite for urinary continence after radical prostatectomy (RP)
is the functional length of the urethral sphincter and the stabilisation of its anatomic position …

Prostate cancer gene 3 (PCA3): development and internal validation of a novel biopsy nomogram

…, Y Fradet, LS Marks, W Ellis, AW Partin, A Haese - European urology, 2009 - Elsevier
BACKGROUND: Urinary prostate cancer gene 3 (PCA3) represents a promising novel marker
of prostate cancer detection. OBJECTIVE: To test whether urinary PCA3 assay improves …

[HTML][HTML] Clinical significance of p53 alterations in surgically treated prostate cancers

…, M Mirlacher, K Milde-Langosch, M Graefen, A Haese… - Modern pathology, 2008 - Elsevier
Despite the high number of previous studies, the role of p53 alterations in prostate cancer is
not clearly defined. To address the role of p53 alterations in prostate cancer biology, a total …