Current molecular combination therapies used for the treatment of breast cancer
Y Wang, A Minden - International journal of molecular sciences, 2022 - mdpi.com
Breast cancer is the second leading cause of death for women worldwide. While
monotherapy (single agent) treatments have been used for many years, they are not always …
monotherapy (single agent) treatments have been used for many years, they are not always …
Low-risk triple-negative breast cancers: Clinico-pathological and molecular features
Triple-negative breast cancers (TNBC) comprise biologically and clinically heterogeneous
diseases characterized by the lack of hormone receptors (HR) and HER2 expression. This …
diseases characterized by the lack of hormone receptors (HR) and HER2 expression. This …
RIPK1-dependent necroptosis promotes vasculogenic mimicry formation via eIF4E in triple-negative breast cancer
F Li, H Sun, Y Yu, N Che, J Han, R Cheng… - Cell Death & …, 2023 - nature.com
Necroptosis is a caspase-independent form of programmed cell death. Receptor interacting
protein kinase 1 (RIPK1) is a key molecule in the initiation of necroptosis and the formation …
protein kinase 1 (RIPK1) is a key molecule in the initiation of necroptosis and the formation …
Long noncoding RNAs in triple‐negative breast cancer: A new frontier in the regulation of tumorigenesis
In recent years, triple‐negative breast cancer (TNBC) has emerged as the most aggressive
subtype of breast cancer and is usually associated with increased mortality worldwide. The …
subtype of breast cancer and is usually associated with increased mortality worldwide. The …
The deubiquitinating enzyme STAMBP is a newly discovered driver of triple-negative breast cancer progression that maintains RAI14 protein stability
Q Yang, D Yan, C Zou, Q Xue, S Lin, Q Huang… - … & Molecular Medicine, 2022 - nature.com
Triple-negative breast cancer (TNBC) is a heterogeneous malignancy in women. It is
associated with poor prognosis, aggressive malignant behavior, and limited treatment …
associated with poor prognosis, aggressive malignant behavior, and limited treatment …
The molecular landscape of breast mucoepidermoid carcinoma
Mucoepidermoid carcinoma (MEC) of the breast is an extremely rare salivary gland‐type
tumor characterized by epidermoid, basaloid, intermediate, and/or mucinous cells arranged …
tumor characterized by epidermoid, basaloid, intermediate, and/or mucinous cells arranged …
[HTML][HTML] Mitochondrial dynamics, a new therapeutic target for Triple Negative Breast Cancer
K Weiner-Gorzel, M Murphy - Biochimica et Biophysica Acta (BBA)-Reviews …, 2021 - Elsevier
Abstract Triple Negative Breast Cancer (TNBC) is an aggressive tumour with patients
survival rarely exceeding five years. TNBC tumours are larger in size, more chemoresistant …
survival rarely exceeding five years. TNBC tumours are larger in size, more chemoresistant …
[HTML][HTML] Shikonin inhibits migration and invasion of triple-negative breast cancer cells by suppressing epithelial-mesenchymal transition via miR-17-5p/PTEN/Akt …
C Bao, T Liu, L Qian, C Xiao, X Zhou, H Ai… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background: Triple-negative breast cancer (TNBC) is a great threat to global women's health
due to its high metastatic potential. Epithelial-to-mesenchymal transition (EMT) is considered …
due to its high metastatic potential. Epithelial-to-mesenchymal transition (EMT) is considered …
Effective suppression of triple negative breast cancer by paclitaxel nanoparticles conjugated with transmembrane TNF-α monoclonal antibody
J Liu, P Wang, B Huang, Q Cheng, Y Duan… - International journal of …, 2022 - Elsevier
Abstract Transmembrane TNF-α (tmTNF), a transmembrane form of TNF-α, was reported
overexpressed in approximately 84% of triple-negative breast cancer (TNBC) patients and …
overexpressed in approximately 84% of triple-negative breast cancer (TNBC) patients and …
Clinical considerations of CDK4/6 inhibitors in triple-negative breast cancer
R Wang, K Xu, F Gao, J Huang, X Guan - Biochimica et Biophysica Acta …, 2021 - Elsevier
The formation of cyclinD-CDK4/6 complex plays vital roles in the cell cycle transition from G1
phase to S phase which is characterized by vigorous transcription and synthesis. Through …
phase to S phase which is characterized by vigorous transcription and synthesis. Through …