Molecular understanding of the protective role of natural products on isoproterenol-induced myocardial infarction: A review

ZW Wong, PV Thanikachalam… - Biomedicine & …, 2017 - Elsevier
Modern medicine has been used to treat myocardial infarction, a subset of cardiovascular
diseases, and have been relatively effective but not without adverse effects. Consequently, this …

More than a drug target: Purinergic signalling as a source for diagnostic tools in epilepsy

ZW Wong, T Engel - Neuropharmacology, 2023 - Elsevier
Epilepsy is one of the most common and disabling chronic neurological diseases affecting
people of all ages. Major challenges of epilepsy management include the persistently high …

[HTML][HTML] Effects of palbociclib on oral squamous cell carcinoma and the role of PIK3CA in conferring resistance

NS Zainal, BKB Lee, ZW Wong, IS Chin… - Cancer biology & …, 2019 - ncbi.nlm.nih.gov
Objective Lack of effective therapies remains a problem in the treatment of oral squamous
cell carcinoma (OSCC), especially in patients with advanced tumors. OSCC development is …

[HTML][HTML] A ratiometric fluorescent biosensor based on magnetic-assisted hybridization chain reaction and DNA-templated silver nanoclusters for sensitive microRNA …

ZW Wong, K Muthoosamy, NAH Mohamed… - … and Bioelectronics: X, 2022 - Elsevier
A biosensor was designed for sensitive detection of microRNA (miR)-144-3p, a potential
miR biomarker for nasopharyngeal cancer, by integrating magnetic beads (MBs) into a …

Current attempts to implement microRNA-based diagnostics and therapy in cardiovascular and metabolic disease: a promising future

…, S Ramamurthy, ZW Wong, BJ Koo, JY Wong… - Drug discovery today, 2018 - Elsevier
Highlights • miRNAs play a major part in the pathogenesis of metabolic disorders such as
diabetes and obesity. • miRNAs additionally serve as biomarkers in the diagnosis, prognosis …

An enzyme-free turn-on fluorescent strategy for nucleic acid detection based on hybridization chain reaction and transferable silver nanoclusters

ZW Wong, SY New - Microchimica Acta, 2023 - Springer
A fluorescence biosensor has been developed based on hybridisation chain reaction (HCR)
amplification coupled with silver nanoclusters (AgNCs) for nucleic acid detection. The …

Ratiometric detection of microRNA using hybridization chain reaction and fluorogenic silver nanoclusters

ZW Wong, JF Ng, SY New - Chemistry–An Asian Journal, 2021 - Wiley Online Library
miRNA (miR)‐155 is a potential biomarker for breast cancers. We aimed at developing a
nanosensor for miR‐155 detection by integrating hybridization chain reaction (HCR) and silver …

High-reflectivity, high-Q micromechanical membranes via guided resonances for enhanced optomechanical coupling

…, SW Hoch, LYT Lee, JGE Harris, C Wei Wong - Applied Physics …, 2012 - pubs.aip.org
Using Fano-type guided resonances (GRs) in photonic crystal (PhC) slab structures, we
numerically and experimentally demonstrate optical reflectivity enhancement of high-Q SiN x …

Radio frequency regenerative oscillations in monolithic high-Q/V heterostructured photonic crystal cavities

…, M Yu, GQ Lo, DL Kwong, C Wei Wong - Applied Physics …, 2014 - pubs.aip.org
We report temporal and spectral domain observation of regenerative oscillation in monolithic
silicon heterostructured photonic crystals cavities with high quality factor to mode volume …

Parametric optomechanical oscillations in two-dimensional slot-type high-Q photonic crystal cavities

…, A Stein, KL Shepard, C Wei Wong - Applied Physics …, 2012 - pubs.aip.org
We experimentally demonstrate an optomechanical cavity based on an air-slot photonic
crystal cavity with optical quality factor Qo ¼4. 2Â104 and a small modal volume of 0.05 cubic …