The ATP-binding cassette transporters (ABC transporters) have been intensely studied over
the past 50 years for their involvement in the multidrug resistance (MDR) phenotype …

Abstract ATP Binding Cassette (ABC) transporters, widely studied in cancer for their role in
drug resistance, have been more recently also considered for their contribution to cancer …

Multidrug transporter proteins are best known for their contributions to chemoresistance
through the efflux of anticancer drugs from cancer cells. However, a considerable body of …

The ATP‐binding cassette (ABC) transporter superfamily is one of the largest membrane
protein families existing in wide spectrum of organisms from prokaryotes to human. ABC …

The extrusion of anticancer drugs by members of the ATP-binding cassette (ABC)
transporter family is one of the most widely recognized mechanisms of multidrug resistance …

Overexpression of ATP-binding cassette (ABC) transporters is a cause of drug resistance in
a plethora of tumors. More recent evidence indicates additional contribution of these …

Background ABC transporters have attracted considerable attention for their function as drug
transporters in a broad range of tumours and are therefore considered as major players in …

Introduction: Most disseminated cancers remain fatal despite the availability of a variety of
conventional and novel treatments including surgery, chemotherapy, radiotherapy …

Enhanced drug extrusion from cells due to the overexpression of the ATP-binding cassette
(ABC) drug transporters inhibits the cytotoxic effects of structurally diverse and …

The adenosine triphosphate binding cassette (ABC) transporters are one of the largest
transmembrane gene families in humans. The ABC transporters are present in a number of …