Microbial-triggered inflammation protects against pathogens and yet can paradoxically
cause considerable secondary damage to host tissues that can result in tissue fibrosis and …

Breast cancer is the most common cancer in women worldwide. Understanding the biology
of this malignant disease is a prerequisite for selecting an appropriate treatment. Cell cycle …

Master developmental pathways, such as Notch, Wnt, and Hedgehog, are signaling systems
that control proliferation, cell death, motility, migration, and stemness. These systems are …

Mesenchymal stromal cells (MSCs) are adult multipotent stem cells residing as pericytes in
various tissues and organs where they can differentiate into specialized cells to replace …

Master developmental pathways, such as Notch, Wnt, and Hedgehog, are signaling systems
that control proliferation, cell death, motility, migration, and stemness. These systems are …

Background Estrogen deficiency is linked to changes in several physiological processes,
but the extent to which it associates with cognitive changes in menopause context is …

B-cell chronic lymphocytic leukemia (CLL), which is the most common lymphoproliferative
disorder, displays characteristics consistent with a defect in programmed cell death and …

Wnts are a family of evolutionary-conserved secreted signaling molecules critically involved
in a variety of developmental processes and in cell fate determination. A growing body of …

Background Cerebral malaria is a rapidly developing encephalopathy caused by the
apicomplexan parasite Plasmodium falciparum. Drugs currently in use are associated with poor …

Breast cancer is the most frequent female malignancy worldwide. Current strategies in
breast cancer therapy, including classical chemotherapy, hormone therapy, and targeted …