Dynamic Contrast-Enhanced MR Imaging in Head and Neck Cancer

Suraj J Kabadi; Girish M Fatterpekar; Yoshimi Anzai; Jonathan Mogen; Mari Hagiwara; Sohil H Patel

doi:10.1016/j.mric.2017.08.008

Dynamic Contrast-Enhanced MR Imaging in Head and Neck Cancer

Magn Reson Imaging Clin N Am. 2018 Feb;26(1):135-149. doi: 10.1016/j.mric.2017.08.008. Epub 2017 Oct 21.

Authors

Suraj J Kabadi¹, Girish M Fatterpekar², Yoshimi Anzai³, Jonathan Mogen⁴, Mari Hagiwara², Sohil H Patel⁵

Affiliations

¹ Diagnostic Radiology, University of Virginia Health System, PO Box 800170, 1215 Lee Street, Charlottesville, VA 22908, USA.
² Department of Radiology, NYU Langone Medical Center, NYU Radiology Associates, 660 First Avenue, 2nd Floor, New York, NY 10016, USA.
³ University of Utah Health, 50 North Medical Drive, Salt Lake City, UT 84132, USA.
⁴ Neuroradiology, NYU Langone Medical Center, NYU Radiology Associates, 660 First Avenue, 2nd Floor, New York, NY 10016, USA.
⁵ Department of Radiology and Medical Imaging, University of Virginia Health System, PO Box 800170, 1215 Lee Street, Charlottesville, VA 22908, USA. Electronic address: shp4k@virginia.edu.

PMID: 29128001
DOI: 10.1016/j.mric.2017.08.008

Abstract

Dynamic contrast-enhanced (DCE) MR imaging uses rapid sequential MR image acquisition before, during, and after intravenous contrast administration to elucidate information on the microvascular biologic function of tissues. The derived pharmacokinetic parameters provide useful information on tissue perfusion and permeability that may help to evaluate entities that otherwise appear similar by conventional imaging. When specifically applied to the evaluation of head and neck cancer, DCE-MR imaging may provide valuable information to help predict treatment response, discriminate between posttreatment changes and residual tumor, and discriminate between various head and neck neoplasms.

Keywords: Dynamic contrast-enhanced MR imaging (DCE-MR imaging); Head and neck cancer (HNC); K(trans); Perfusion; Permeability; Squamous cell cancer (SCC); Time intensity curve (TIC); Treatment response.

Publication types

Review

MeSH terms

Contrast Media*
Head / diagnostic imaging
Head and Neck Neoplasms / diagnostic imaging*
Humans
Image Enhancement / methods*
Magnetic Resonance Imaging / methods*
Neck / diagnostic imaging

Substances

Contrast Media