Improved breast cancer detection in asymptomatic women using 3D-automated breast ultrasound in mammographically dense breasts

Clin Imaging. 2013 May-Jun;37(3):480-6. doi: 10.1016/j.clinimag.2012.09.018. Epub 2012 Oct 30.

Abstract

Automated breast ultrasound (ABUS)was performed in 3418 asymptomatic women with mammographically dense breasts. The addition of ABUS to mammography in women with greater than 50% breast density resulted in the detection of 12.3 per 1,000 breast cancers, compared to 4.6 per 1,000 by mammography alone. The mean tumor size was 14.3 mm and overall attributable risk of breast cancer was 19.92 (95% confidence level, 16.75 - 23.61) in our screened population. These preliminary results may justify the cost-benefit of implementing the judicious us of ABUS in conjunction with mammography in the dense breast screening population.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Algorithms
  • Artificial Intelligence
  • Breast Neoplasms / diagnostic imaging*
  • Breast Neoplasms / epidemiology*
  • Densitometry / statistics & numerical data*
  • Female
  • Florida / epidemiology
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Middle Aged
  • Pattern Recognition, Automated / methods*
  • Prevalence
  • Reproducibility of Results
  • Risk Assessment
  • Sensitivity and Specificity
  • Ultrasonography, Mammary / statistics & numerical data*
  • Young Adult