Vol 15, Suppl 1: November 2018 (Abstract collection of 2018 Beijing Liver Cancer International Conference)

Table of Contents

Basic and translational research on liver cancer

Comprehensive identification of key biomarkers and pathways in hepatitis B virus-related hepatocellular carcinoma using bioinformatic analyses
Xiwen Liao, Tao Peng 1
Integrated analysis of the competing endogenous RNA network to identify the potential prognostic biomarkers in hepatocellular carcinoma
Xiwen Liao, Tao Peng 1
Identification of potential prognostic microRNA biomarkers for predicting survival in patients with hepatocellular carcinoma
Xiwen Liao, Tao Peng 1
Role of ELMOs in cancer cell migration and engulfment
Hongyan Li, Yinying Lu, Ning Zhang, Fei Li 2
Pretreatment prediction of Immunoscore in hepatocellular cancer: a radiomics-based clinical nomogram based on Gd- EOB-DTPA enhanced-MRI
Shuling Chen, Shiting Feng, Han Xiao, Mimi Tang, Zhihang Chen, Sui Peng, Ming Kuang 2
Post-surgery multiple-site sampling procedure for the precise detection of microvascular invasion of hepatocellular carcinoma
Shuling Chen, Lili Chen, Qian Zhou, Mimi Tang, Han Xiao, Sui Peng, Bing Liao, Ming Kuang 2
Bile acids and sphingolipids in cholangiocarcinoma
Runping Liu, Renping Zhao, Phillip B. Hylemon, Huiping Zhou 3
Role of the melatonin/menin signaling in the regulation of cholangiocarcinoma growth
Shannon Glaser, Gianfranco Alpini 3
MicroRNA-regulated cancer stemness in the patientderived xenograft model of human cholangiocarcinoma
Kelly McDaniel, Sugeily Lorenzo, Heather Francis, Gianfranco Alpini, Fanyin Meng 4
A critical role of HMGB1 in liver tumor development under autophagy deficiency
Xiaoming Yin, Khambu B, Nazmul Huda 4
Differential expression of APE1 in hepatocellular carcinoma and the corresponding effects on proliferation and apoptosis of cancer cells
Zhipeng Sun, Nengwei Zhang 5
Platinum-based nanopharmaceuticals used to overcome cisplatin resistance in vitro and in vivo
Xingjie Liang 5
Roles of γδ T cells in the hepatocellular carcinoma
Na Zhao, Hien Dang, Lichun Ma, Xinwei Wang 5
NLRP6 is correlated with the progression and therapeutic outcome of hepatocellular carcinoma and inhibits the function of CD14+ cells
Ting Zhang, Gang Chen, Lifeng Wang, Xinrui Yang, Dawei Wu, Shanshan Lu, Yinying Lu, Zhen Zeng 6
A novel fibroblast growth factor 15-dependent and bile acid-independent promotion of liver regeneration in mice
Bo Kong, Ruibing Sun, Mingxing Huang, Monica Chow, Xiaobo Zhong, Wen Xie, Yi-Horng Lee, Grace L. Guo 6
Integrative molecular analysis of hepatocellular carcinoma by HCCDB
Qiuyu Lian, Shicheng Wang, Dongfang Wang, Jin Gu 7
Reducing the incidence of hepatocellular carcinoma due to hepatitis C virus infection by detecting resistanceassociated substitutions in hepatitis C virus NS5A nonstructural protein
RozainaneeMohd Zain, Nurul Asshikin Ruslan, Sairulahkma Awang, Muhammad Adib Abd Wahab, Ravindran Thayan 7
An efficient combination immunotherapy for liver cancer by remodeling innate and adaptive immunity
Gensheng Feng 7
TRAF7 enhances degradation of ubiquitinated KLF4 to promote hepatocellular carcinoma progression
Huan He, Zhiyuan Wu, Sheng Li, Dongmei Wang, Zhihua Liu, Chunfeng Qu 8
Serum CA125, CA199, CEA, CA724, and AFP for diagnosis and prognosis prediction in patients with intrahepatic cholangiocarcinoma
Shanshan Lu, Ning Zhang, Xiaodong Jia, Ting Zhang, Xinrui Yang, Jie Sun, Zhen Zeng, Yinying Lu 8
Preoperative prediction of microvascular invasion in hepatocellular cancer: a radiomics model using Gd-EOB-DTPA- enhanced MRI
Zhenwei Peng, Shuling Chen, Mimi Tang, Qian Zhou, Zebin Chen, Ming Kuang 9
Prognostic nomograms on inflammatory markers in hepatitis B virus-related hepatocellular carcinoma patients who underwent hepatectomy
Yifei Wang, Shuling Chen, Bin Li, Zebin Chen, Zhenwei Peng, Ming Kuang 9
Abnormal accumulation of RNA helicase DDX5 protein promotes malignancy of hepatocellular carcinoma
Ting Zhang, Xinrui Yang, Wanping Xu, Weiping Zhou, Shengxian Yuan, Jing Wang, Zhen Zeng, Dawei Wu, Yinyin Li, Xiaodong Jia, Shanshan Lu, Ze Liu, Wenlin Bai, Jinke Dong, Rifaat Safadi, Cuihong Zhang, Yinying Lu 10
Common molecular subtypes among Asian hepatocellular carcinoma and cholangiocarcinoma
Jittiporn Chaisaingmongkol, Anuradha Budhu, Hien Dang, Siritida Rabibhadana, Benjarath Pupacdi, So Mee Kwon, Marshonna Forgues, Yotsawat Pomyen, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Anon Chotirosniramit, Chawalit Pairojkul, Chirayu U. Auewarakul, Thaniya Sricharunrat, Kannika Phornphutkul, Suleeporn Sangrajrang, Maggie Cam, Ping He, Stephen M. Hewitt, Kris Ylaya, Xiaolin Wu, Jesper B. Andersen, Snorri S. Thorgeirsson, Joshua J. Waterfall, Yuelin J. Zhu, Jennifer Walling, Holly S. Stevenson, Daniel Edelman, Paul S. Meltzer, Christopher A. Loffredo, Natsuko Hama, Tatsuhiro Shibata, Robert H. Wiltrout, Curtis C. Harris, Chulabhorn Mahidol, Mathuros Ruchirawat, Xinwei Wang 10
Mouse avatar models derived from patients with colorectal cancer liver metastases provide a wellcharacterized platform for preclinical studies
Jingyuan Wang, Wei Liu, Jing Gao, Baocai Xing, Lin Shen 11
Lymph node metastasis of hepatocellular carcinoma is associated with gut microbiota, bile acid metabolism and inflammation
Xiaodong Jia, Shanshan Lu, Zhen Zeng, Ting Zhang, Yinyin Li, Zheng Dong, Xinrui Yang, Cuihong Zhang, Jinke Dong, Dawei Wu, Junfan Bai, Jiao Xiang, Yinying Lu 11
Arginine methylation by PRMT6 as a novel stemness and metabolic regulator in hepatocellular carcinoma
Stephanie Ma 12
Pathway analysis of metabolic genes and serum metabolites in HCC reveal aberrations associated with fatty acid and lipid metabolism
Yotsawat Pomyen, Anuradha Budhu, Jittiporn Chaisaingmongkol, Hien Dang, Siritida Rabibhadana, Benjarath Pupacdi, Marshonna Forgues, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Chirayu Auewarakul, Thaniya Sricharunrat, Kannika Phornphutkul, Suleeporn Sangrajrang, Chulabhorn Mahidol, Mathuros Ruchirawat, Xinwei Wang 12
Pathway analysis of metabolic genes and serum metabolites in HCC reveal aberrations associated with fatty acid and lipid metabolism
Yotsawat Pomyen, Anuradha Budhu, Jittiporn Chaisaingmongkol, Hien Dang, Siritida Rabibhadana, Benjarath Pupacdi, Marshonna Forgues, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Chirayu Auewarakul, Thaniya Sricharunrat, Kannika Phornphutkul, Suleeporn Sangrajrang, Chulabhorn Mahidol, Mathuros Ruchirawat, Xinwei Wang 12
MiRNAs in hepatic tumor-initiating cells
Junfang Ji 13
Global tissue and serum metabolomics reveals altered tumor biochemical activity in molecular subtypes of hepatocellular carcinoma and cholangiocarcinoma
Xinwei Wang, Thaniya Mathuros Ruchirawat, Anuradha Budhu, Yotsawat Pomyen, Jittiporn Chaisaingmongkol, Hien Dang, Siritida Rabibhadana, Benjarath Pupacdi, Marshonna Forgues, Vajarabhongsa Bhudhisawasdi, Nirush Lertprasertsuke, Anon Chotirosniramit, Chawalit Pairojkul, Chirayu Auewarakul, Thaniya Sricharunrat, Kannika Phornphutkul, Suleeporn Sangrajrang, Chulabhorn Mahidol 13
The dilemmas of liver cancer heterogeneity
Xinwei Wang 14
Aldehyde dehydrogenase 2 suppresses cirrhosis and alcohol-induced hepatocellular carcinoma via the inhibition of acetaldehyde-derived DNA damage and multiple oncogenic signaling pathways
Bin Gao, Wonhyo Seo, Yanhang Gao, Tianyi Ren, Seungjin Kim, Yong He, Dechun Feng, Junqi Niu 14
Interleukin-17 mediates liver progenitor cell transformation into cancer stem cells through downregulation of miR-122
Imène Gasmi, Camilia Machou, Aurélie Rodrigues, Julien Calderaro, Benoit Rousseau, Arthur Brouillet, Christophe Rodriguez, Vanessa Demontant, Guillaume Gricourt, Alain Luciani, Jean-Michel Pawlotsky, Fouad Lafdil 14
Genetic profiling of aflatoxin-associated hepatocellular carcinoma and its application in liquid biopsy
Yuchen Jiao 15
Metabolism regulation of TD26 in hepatocellular carcinoma: mechanistic links and potential clinical implication
Chenchen Wang, Jie Cai, Hailong Wu, Xiaoni Kong, Qiang Xia 15
Identification of potential long non-coding RNA biomarkers to predict the survival of patients with hepatocellular carcinoma
Xiwen Liao, Tao Peng 16
Discrimination of clonal origin patterns for molecular pathological diagnosis of RHCC/MHCC
Wenming Cong, Mengchao Wu 16
Development of CAR T cell therapy targeting glypican-3 in liver cancer
Dan Li, Nan Li, Yifan Zhang, Haiying Fu, Madeline B. Torres, Tim F. Greten, Mitchell Ho 17
FRNK negatively regulates liver fibrosis via attenuating activation of hepatic stellate cells
Gaoliang Zou, Xueke Zhao 17
XCL1/Glypican-3 fusion protein induces potent CD8+ T-cell generation and enhances the anti-PD1 effect to suspend hepatocellular carcinoma development
Kun Chen, Yanmei Wang, Hong Zhao, Zhiyuan Wu, Xinyu Bi, Jianguo Zhou, Dongmei Wang, Jianqiang Cai, Chunfeng Qu 17
Efficient combination immunotherapy for liver cancer using harmonized activation of innate and adaptive immunity
Liang Wen, Gaowei Wang, Chia-Hao Lin, Panyisha Wu, Chuanhui Peng, Jin Lee, Lifan Lu, Gensheng Feng 18
Incomplete RFA of HCC promotes intrahepatic metastasis and stemness in a VEGFR1-dependent manner
Li Tan, Guangyan Wei, Ying Zou, Junbin Liao, Manlin Huang, Lixia Xu, Sui Peng, Ming Kuang 18
NK cell checkpoints and immune therapy in fatty liver disease
Rifaat SAFADI 19
Lower risk of hepatocellular carcinoma among patients with chronic hepatitis B treated with tenofovir than entecavir
Young-Suk Lim 19
Apatinib radiosensitizes hepatocellular carcinoma in vitro and in vivo
Huilin Jin, Junbin Liao, Lixia Xu, Qi Zhou, Sui Peng, Ming Kuang 20

Clinical treatment of liver cancer

Efficacy evaluation of microwave ablation in primary hepatic carcinoma after 5 years
Lu Zhao, Xingjun Zhuang 21
Analysis of the therapeutic effect of transhepatic arterial embolization combined with microwave ablation for hepatic epithelioid hemangioendothelioma
Jianjun Li 21
Cryoablation of hepatocellular carcinoma with high-risk percutaneous ablation
Jongyun Won 21
Application of microvascular invasion at primary resection in treatment selection for intermediate-advanced recurrent hepatocellular carcinoma
Zebin Chen, Yuanqi Wang, Shuling Chen, Sui Peng, Zhenwei Peng, Ming Kuang 21
Tumor size and location affect the treatment selection for solitary small recurrent hepatocellular carcinoma after initial hepatectomy
Zhenwei Peng, Shuling Chen, Mengchao Wei, Han Xiao, Zebin Chen, Ming Kuang 22
Novel nomogram model for predicting severe posthepatectomy liver failure risk in patients with resectable hepatocellular carcinoma
Rongyun Mai, Jiazhou Ye, Zhongrong Long, Xianmao Shi, Tao Bai, Lequn Li, Feixiang Wu, Guobin Wu 22
Nomogram for preoperative estimation of liver cirrhosis in hepatitis B virus-related hepatocellular carcinoma patients
Rongyun Mai, Jiazhou Ye, Rong Liang, Jie Zeng, Zhongrong Long, Xianmao Shi, Tao Bai, Lequn Li, Guobin Wu, Feixiang Wu 23
Efficacy evaluation of DynaCT-assisted DEB-TACE in the treatment of primary liver cancer
Shangwei Ji, Gang Zuo, Yu Sun 23
Recent experience of 70 pediatric living donor liver transplants (LDLTs): arterial reconstruction
Michael Gurevich 24
Innovative management of the open abdomen: ultrasound Doppler-guided gradual abdominal wall closure after pediatric liver transplantation
Michael Gurevich, Moris Topaz 24
Current status and future of systemic therapy for hepatocellular carcinoma
Ghassan Abou-Alfa 25
Precision surgery for primary liver cancer
Masatoshi Makuuchi 25


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