Estimation of lung cancer burden in Australia, the Philippines, and Singapore: an evaluation of disability adjusted life years

Suman Morampudi, Neha Das, Arun Gowda, Anand Patil

Abstract


Objective: Lung cancer is one of the leading cancers and major causes of cancer mortality worldwide. The economic burdenassociated with the high mortality of lung cancer is high, which accounts for nearly $180 billion on a global scale in 2008. This paper aims to understand the economic burden of lung cancer in terms of disability adjusted life years (DALY) in Australia, thePhilippines, and Singapore.

Methods: The years of life lost (YLL) and years lost due to disability (YLD) were calculated using the formula developed byMurray and Lopez in 1996 as part of a comprehensive assessment of mortality and disability for diseases, injuries and risk factorsin 1990 and projected to 2020. The same formula is represented in the Global Burden of Disease template provided by the WorldHealth Organization. Appropriate assumptions were made when data were unavailable and projections were performed usingregression analysis to obtain data for 2015.

Results: The total DALYs due to lung cancer in Australia, the Philippines, and Singapore were 91,695, 38,584, and 12,435,respectively, and the corresponding DALY rates per a population of 1,000 were 4.0, 0.4, and 2.2, respectively, with a discount rateof 3%. When researchers calculated DALYs without the discount rate, the burden of disease increased substantially; the DALYswere 117,438 in Australia, 50,977 in the Philippines, and 16,379 in Singapore. Overall, YLL or premature death accounted for morethan 95% of DALYs in these countries.

Conclusions: Strategies for prevention, early diagnosis, and prompt treatment must be devised for diseases where the majorburden is due to mortality.


Keywords


Lung cancer; DALY; YLD; YLL; burden of disease; DALY rate; discount rate

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