Table 1

Demographic information and MSI/MMR status for recruited patients

	Total (n = 1,923)	%	P (n = 85)	%	LP (n = 62)	%	non-P (n = 1,776)	%	P (P vs. non-P)	P (LP vs. non-P)
Stage									0.13	0.00032
I	183	0.095	2	0.024	1	0.016	180	0.101
II	833	0.433	39	0.459	37	0.597	757	0.426
III	527	0.274	25	0.294	6	0.097	496	0.279
IV	380	0.198	19	0.224	18	0.29	343	0.193
Age									0.001	0
<40	182	0.095	16	0.188	4	0.065	162	0.091
40–49	332	0.173	21	0.247	25	0.403	286	0.161
50–59	511	0.266	18	0.212	14	0.226	479	0.270
≥60	810	0.421	25	0.294	15	0.242	770	0.434
NA	88	0.046	5	0.059	4	0.065	79	0.044
Gender									0.458	0.288
Male	1130	0.588	52	0.612	33	0.532	1045	0.588
Female	728	0.379	28	0.329	28	0.452	672	0.378
NA	65	0.034	5	0.059	1	0.016	59	0.033
Family history									0.014	0.026
Yes	111	0.058	8	0.094	7	0.113	96	0.054
No	734	0.382	21	0.247	19	0.306	694	0.391
NA	1078	0.561	56	0.659	36	0.581	986	0.555
MSI status									0	0
MSI-H	113	0.059	25	0.294	18	0.290	68	0.038
MSI-L	21	0.011	2	0.024	2	0.032	17	0.010
MSS	1577	0.820	47	0.553	38	0.613	1492	0.840
NA	214	0.111	11	0.129	4	0.065	199	0.112
MMR status									0	0
dMMR	82	0.043	19	0.224	15	0.242	48	0.027
pMMR	750	0.390	27	0.318	11	0.177	712	0.401
NA	1091	0.567	39	0.459	36	0.581	1016	0.572

P, pathogenic; LP, likely pathogenic; non-P, non-pathogenic; MSI, microsatellite instability; MSI-H, microsatellite instability high; MSI-L, microsatellite instability low; MSS, macrosatellite stable; MMR, mismatch repair; dMMR, deficient mismatch repair; pMMR, proficient mismatch repair; NA, not available.