Multivariate Cox proportional hazard models predicting PFS for patients receiving combined therapy
| Variables | HR (95% CI) | P value |
|---|---|---|
| Age (< 55/≥ 55) | 1.106 (0.513–2.383) | 0.798 |
| Hormone receptor (neg/pos) | 0.716 (0.320–1.604) | 0.417 |
| ECOG PS (0/1) | 0.249 (0.085–0.734) | 0.012 |
| Apatinib initial dose (425 mg/500 mg) | 0.838 (0.306–2.297) | 0.732 |
| Proteinuria (no/yes) | 1.349 (0.596–3.053) | 0.472 |
| Delayed administration (no/yes) | 5.065 (1.909–13.435) | 0.001 |
PFS, progression free survival; ECOG PS, Eastern Cooperative Oncology Group Performance Statues.