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Clinicopathologic variables and the expression status of LAG-3 in soft tissue sarcoma

Clinicopathological parametersLAG-3 expression P
Low n (%) High n (%)
Age (years) 0.100
> 65131 (87.9)18 (12.1)
≥ 6510 (71.4)4 (28.6)a
Gender 0.165
Male78 (83.0)16 (17.0)
Female63 (91.3)6 (8.7)
Tumor depth 0.017*
Superficial102 (82.9)21 (17.1)
Deep39 (97.5)1 (2.5)a
Grade < 0.001 **
Low grade (G1+G2)114 (92.7)9(7.3)
High grade (G3)27(67.5)13 (32.5)
Site 1.000
Trunk & extremity47 (87.0)7 (13.0)
Head/neck & intra-
abdominal
94 (86.2)15 (13.8)
Stage 0.016 *
I+II119 (90.2)13 (9.8)
III+IV22 (71.0)9 (29.0)

a: Fisher test was used when n < 5; * P < 0.05; ** P < 0.01