Table 2

Clinical trials of anti-LAG-3/Tim-3 on GBM

Clin. Trial IDDiseaseInterventionsStatusPhaseCompletion dataResult
NCT02658981GBM, gliosarcoma recurrent brain neoplasmAnti-LAG-3 alone in combination with nivolRecruitPhase IDec. 2020Unfinished
NCT03493932GBMAnti-LAG-3 combined with nivolRecruitPhase IJun. 2021Unfinished
NCT03961971GBM, multiformeAnti-Tim-3 in combination with anti-PD1 and SRS (stereotactic radiosurgery)Not yet recruitPhase IJun. 2023Unfinished